ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2013
HIZ's relation to axial load and low back pain: investigated with axial loaded MRI and pressure controlled discography.
Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Coexistence of Vertebral and Intervertebral Disc Changes in Low Back Pain Patients-In Depth Characterization with Same Day MRI and CT Discography.Diagnostics (Basel, Switzerland) · 2023Article
- Associations between Vertebral Localized Contrast Changes and Adjacent Annular Fissures in Patients with Low Back Pain: A Radiomics Approach.Journal of clinical medicine · 2023Article
- Low back pain of disc, sacroiliac joint, or facet joint origin: a diagnostic accuracy systematic review.EClinicalMedicine · 2023Article
- Clinical outcome and MRI appearance in a group of chronic low back pain patients more than 10 years after discography evaluation and consideration for surgery.BMC musculoskeletal disorders · 2023Article
- Detection of Imperceptible Intervertebral Disc Fissures in Conventional MRI-An AI Strategy for Improved Diagnostics.Journal of clinical medicine · 2022Article
- Predictors of discogenic pain in magnetic resonance imaging: a retrospective study of provocative discography performed by posterolateral approach.The Korean journal of pain · 2021Article
- Intradiscal quantitative chemical exchange saturation transfer MRI signal correlates with discogenic pain in human patients.Scientific reports · 2021Observational
- The relevance of high-intensity zones in degenerative disc disease.International orthopaedics · 2019Review
- Low Back Pain in Adolescent Athletes: Comparison of Diagnoses Made by General Orthopedic Surgeons and Spine Surgeons.International journal of spine surgery · 2019Article
- Differences in IVD characteristics between low back pain patients and controls associated with HIZ as revealed with quantitative MRI.PloS one · 2019Article
- MRI histogram analysis enables objective and continuous classification of intervertebral disc degeneration.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2018Article
- Operative Management of Lumbar Degenerative Disc Disease.Asian spine journal · 2016Review
- Comparison between pain at discography and morphological disc changes at axial loaded MRI in patients with low back pain.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2014Article
- The Michel Benoist and Robert Mulholland Yearly European Spine Journal Review: a survey of the "surgical and research" articles in the European Spine Journal, 2013.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2014Review
Corrections and comments
- Erratum issuedHanna, Hebelka [corrected to Hebelka, Hanna]; Tommy, Hansson [corrected to Hansson, Tommy]
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe aims were to investigate if the detection of high-intensity zones (HIZ) is affected by axial load, and to study the correlation between HIZ and discogenic pain provoked with pressure controlled discography (PCD).
methods41 consecutive patients with chronic low back pain, referred for discography, were included. Each patient underwent PCD, CT, MRI, and axial loaded MRI (alMRI) within 24 h. 35 patients completed all MRI sequences (140 discs). The detection of HIZ was compared between conventional MRI and alMRI. PCD was performed in 119 of the discs examined at MRI. Provoked pain at PCD was classified into four categories (none/unfamiliar/similar/exact), with the patients' daily pain as reference, and correlated with presence of HIZ.
resultsAlMRI did not affect the detection of HIZ compared with conventional MRI. No significant correlation between HIZ and the 4-graded pain response at discography was found (p = 0.34), neither when combining similarly/exactly reproduced pain (p = 0.08). The sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of HIZ in detecting discs with exactly reproduced pain were 49, 69, 39 and 76 %. When combining similarly/exactly reproduced pain, PPV was higher but still only 70 %.
conclusionsThe detection of HIZ was not influenced by axial load. With strict PCD, discogenic pain can neither be confirmed when having HIZ (PPV 39 %) nor ruled out in discs without HIZ (NPV 76 %). Larger PCD studies including quantification of HIZ at conventional and alMRI are needed, before any dynamic component affected by axial load can be ruled out completely.
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