ArticleMedical & biological engineering & computing2012
Fluctuation analysis of respiratory impedance waveform in asthmatic patients: effect of airway obstruction.
Article in Medical & biological engineering & computing, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Physiological signal entropy in patients with chronic respiratory disease: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2025Pooled it
- Fluctuation Analysis of Peak Expiratory Flow and Its Association with Treatment Failure in Asthma.American journal of respiratory and critical care medicine · 2017Trial
- Combined forced oscillation and fractional-order modeling in patients with work-related asthma: a case-control study analyzing respiratory biomechanics and diagnostic accuracy.Biomedical engineering online · 2020Article
- COPD Patients Have a Restricted Breathing Pattern That Persists with Increased Metabolic Demands.COPD · 2020Article
- Handgrip Strength and Pulmonary Disease in the Elderly: What is the Link?Aging and disease · 2019Review
- Entropy Analysis for the Evaluation of Respiratory Changes Due to Asbestos Exposure and Associated Smoking.Entropy (Basel, Switzerland) · 2019Article
- Article
- Entropy Change of Biological Dynamics in Asthmatic Patients and Its Diagnostic Value in Individualized Treatment: A Systematic Review.Entropy (Basel, Switzerland) · 2018Review
- The development of a novel knowledge-based weaning algorithm using pulmonary parameters: a simulation study.Medical & biological engineering & computing · 2018Article
- A simple method to reconstruct the molar mass signal of respiratory gas to assess small airways with a double-tracer gas single-breath washout.Medical & biological engineering & computing · 2017Article
- Systems Biology and Clinical Practice in Respiratory Medicine. The Twain Shall Meet.American journal of respiratory and critical care medicine · 2016Article
- Brazilian studies on pulmonary function in COPD patients: what are the gaps?International journal of chronic obstructive pulmonary disease · 2016Review
- Article
- What long-term changes in lung function can tell us about asthma control.Current allergy and asthma reports · 2015Review
- Neuro-fuzzy classification of asthma and chronic obstructive pulmonary disease.BMC medical informatics and decision making · 2015Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fluctuation analysis has great potential to contribute to pulmonary clinical science and practice. We evaluated the relationship between asthma and the respiratory impedance recurrence period density entropy (RPDEnZrs) and the variability (SDZrs). A non-invasive and simple protocol for assessing respiratory mechanics during spontaneous breathing was used in a group of 74 subjects with various levels of airway obstruction. Airway obstruction resulted in a reduction in the RPDEnZrs that was significantly correlated with both spirometric indices of airway obstruction (R = 0.48, p < 0.0001) and mean respiratory impedance (R = -0.83, p < 0.0001). These results suggest that the impedance pattern becomes less complex in asthmatic patients, which may explain the reduction in respiratory systems' adaptability to daily life activities. Preliminary evaluations indicate that RPDEnZrs may contribute to the asthma diagnosis, presenting accuracies of 82 and 87 % in patients with moderate and severe airway obstruction, respectively. On the other hand, SDZrs increased with obstruction (p < 0.0001) and was inversely correlated with spirometric indices of obstruction (R = -0.42, p = 0.0003) and directly associated with mean impedance (R = 0.88, p < 0.0001). This analysis contributes to elucidate previous studies and identified respiratory changes in patients with moderate and severe obstruction with an adequate accuracy (85 and 87 %, respectively).
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Registered trials
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