ArticleThe Pediatric infectious disease journal2013
Group B Streptococcus and Escherichia coli infections in the intensive care nursery in the era of intrapartum antibiotic prophylaxis.
Article in The Pediatric infectious disease journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 64 citations in OpenAlex.
- Benefits and Harms of Antenatal/Intrapartum Screening for Maternal Group B Streptococcus and Use of Intrapartum Antibiotic Prophylaxis Versus Risk-Based Protocols or No Intervention: A Rapid Review.Acta paediatrica (Oslo, Norway : 1992) · 2026Review
- Article
- Comparing procalcitonin and C-reactive protein levels in very low birth weight infants with sepsis.Pediatric research · 2026Article
- Duration of Antibiotic Therapy forThe journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2026Article
- Duration of Antibiotic Therapy forThe journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2026Article
- Research Progress on perinatalFrontiers in microbiology · 2026Review
- Epidemiology and outcomes of bacterial meningitis in the neonatal intensive care unit.Journal of perinatology : official journal of the California Perinatal Association · 2024Article
- Intrapartum antibiotic prophylaxis to prevent Group B streptococcal infections in newborn infants: a systematic review and meta-analysis comparing various strategies.EClinicalMedicine · 2024Article
- Predictive factors for perinatal bacterial transmission from colonized mothers to delivered very-low-birth-weight infants: a retrospective cohort study.Scientific reports · 2024Article
- Vaginal carriage of Haemophilus influenzae in a non-pregnant reproductive-age population.BMC microbiology · 2023Article
- Metabolic and Morphotypic Trade-Offs within the Eco-Evolutionary Dynamics of Escherichia coli.Microbiology spectrum · 2022Article
- Relationship Between Antibiotic Resistance, Biofilm Formation, and Biofilm-Specific Resistance inInfection and drug resistance · 2022Article
- Maternal Obesity and Risk of Early-onset Neonatal Bacterial Sepsis: Nationwide Cohort and Sibling-controlled Studies.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021Article
- Genome-Wide fitness analysis of group B Streptococcus in human amniotic fluid reveals a transcription factor that controls multiple virulence traits.PLoS pathogens · 2021Article
- Early-onset neonatal sepsis: Organism patterns between 2009 and 2014.Paediatrics & child health · 2020Article
- Closer and closer? Maternal immunization: current promise, future horizons.Journal of perinatology : official journal of the California Perinatal Association · 2020Review
- Clinical and Bacteriological Profile of Neonatal Sepsis: A Prospective Hospital-Based Study.International journal of pediatrics · 2020Article
- Should clinical suspicion shift to ampicillin resistance organisms in certain preterm premature rupture of membranes scenarios?: Case of early-onset sepsis caused byClinical case reports · 2019Article
- Neonate Bloodstream Infections in Organization for Economic Cooperation and Development Countries: An Update on Epidemiology and Prevention.Journal of clinical medicine · 2019Review
- The cut-off levels of procalcitonin and C-reactive protein and the kinetics of mean platelet volume in preterm neonates with sepsis.BMC pediatrics · 2018Article
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 2 countries.
Funding
Abstract
backgroundGroup B Streptococcus (GBS) and Escherichia coli cause serious bacterial infections (SBIs) and are associated with morbidity and mortality in newborn infants. Intrapartum antibiotic prophylaxis reduces early-onset SBIs caused by GBS. The effect of intrapartum antibiotic prophylaxis on late-onset SBIs caused by these organisms is unknown.
methodsWe examined all blood, urine and cerebrospinal fluid culture results from infants admitted from 1997 to 2010 to 322 neonatal intensive care units managed by the Pediatrix Medical Group. We identified infants with positive cultures for GBS or E. coli and compared the incidence of early- and late-onset SBI for each organism in the time period before (1997 to 2001) and after (2002 to 2010) universal intrapartum antibiotic prophylaxis recommendations.
resultsWe identified 716,407 infants with cultures, 2520 (0.4%) with cultures positive for GBS and 2476 (0.3%) with cultures positive for E. coli. The incidence of GBS early-onset SBI decreased between 1997 to 2001 and 2002 to 2010 from 3.5 to 2.6 per 1000 admissions, and the incidence for E. coli early-onset SBI remained stable (1.4/1000 admissions in both time periods). Over the same time period, the incidence of GBS late-onset SBI increased from 0.8 to 1.1 per 1000 admissions, and incidence of E. coli late-onset SBI increased from 2.2 to 2.5 per 1000 admissions.
conclusionsIn our cohort, the incidence of GBS early-onset SBI decreased, whereas the incidence of late-onset SBI for E. coli and GBS increased.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.