Evidence map›Paper›PMID 23010876›Full record

ReviewNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2013

Toxoplasmosis and neuropsychiatric diseases: can serological studies establish a clear relationship?

Silvia Fabiani, Barbara Pinto, Fabrizio Bruschi

Abstract readReview
PubMed Publisher
In one paragraph

Review in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Global seroprevalence ofHealth science reports · 2023
    Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Toxoplasma infection in individuals in central Italy: does a gender-linked risk exist?European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2017
    Article
  11. Is Toxoplasma gondii a Trigger of Bipolar Disorder?Pathogens (Basel, Switzerland) · 2017
    Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Spinal cord pathology in chronic experimental Toxoplasma gondii infection.European journal of microbiology & immunology · 2014
    Article
  17. Article
  18. Article
  19. Toxoplasma gondii and neuropsychiatric diseases: strain hypothesis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2013
    Article
  20. Molecular and Serological Detection ofIranian journal of parasitology
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Silvia FabianiDepartment of Experimental Pathology, M.B.I.E., School of Medicine, Università di Pisa, Via Roma, 55 Pisa, Italy.
Barbara Pinto
Fabrizio Bruschi

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Toxoplasmosis is a widespread infection, with clinical spectrum ranging from a completely asymptomatic infection to multi-organ involvement. After entering the body, the parasite forms tissue cysts and establishes a chronic infection, involving also the central nervous system (CNS). During the last years, a lot of research has focused on the possible link between exposure to T. gondii and development of neuropsychiatric disorders such as schizophrenia and Parkinson's disease (PD). If a firm association between Toxoplasma infection and neuropsychiatric disorders will be established, this would lead to novel strategies for their prevention and treatment. We will review data from serological and neurodevelopment studies relating infection with T. gondii to such neuropsychiatric diseases.

Indexed as

Mental DisordersNervous System DiseasesAntibodies, ProtozoanHumansProtozoan ProteinsSerologic TestsToxoplasmaToxoplasmosisAntibodies, ProtozoanProtozoan Proteins

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.