Evidence map›Paper›PMID 23010779›Full record

Trial reportEating and weight disorders : EWD2012

Diet type and changes in food cravings following weight loss: findings from the POUNDS LOST Trial.

S D Anton, J Gallagher, V J Carey, N Laranjo, J Cheng, C M Champagne, D H Ryan, K McManus, C M Loria, G A Bray and 2 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Eating and weight disorders : EWD, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 4 pooled it
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 4 syntheses or guidelines pooled it, 41 citations in OpenAlex.

  1. Pooled it
  2. Reduction in saturated fat intake for cardiovascular disease.The Cochrane database of systematic reviews · 2020
    Pooled it
  3. Reduction in saturated fat intake for cardiovascular disease.The Cochrane database of systematic reviews · 2020
    Pooled it
  4. Extended calorie restriction suppresses overall and specific food cravings: a systematic review and a meta-analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2017
    Pooled it
  5. Trial
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  11. Article
  12. Article
  13. Article
  14. Review
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  16. Article
  17. Review
  18. Food cravings and body weight: a conditioning response.Current opinion in endocrinology, diabetes, and obesity · 2018
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

S D AntonPennington Biomedical Research Center, LSU System, Baton Rouge, LA, USA. santon@aging.ufl.edu
J Gallagher
V J Carey
N Laranjo
J Cheng
C M Champagne
D H Ryan
K McManus
C M Loria
G A Bray
F M Sacks
D A Williamson
Harvard University · USPennington Biomedical Research Center · USUniversity of Florida · USLouisiana State University System · USNational Institutes of Health · US

Funding

Zoledronic Acid in Treatment of Osteoporosis in PostmenoM01RR002635 · NCRR · BRIGHAM AND WOMEN'S HOSPITAL · PI WELT, CORRINE K · 1985 to 2008
$48.4M
Research BaseP30DK072476 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI ROBERT A KESTERSON · 2005 to 2026
$26.5M
University of Florida Older Americans Independence Center (OAIC)P30AG028740 · NIA · UNIVERSITY OF FLORIDA · PI Peihua Qiu · 2007 to 2026
$22.8M
Dietary Macronutrients and Weight LossU01HL073286 · NHLBI · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI SACKS, FRANK M · 2003 to 2008
$7.6M
Investigations of botanicals on food intake, satiety, weight loss, and oxidativeK23AT004251 · NCCIH · UNIVERSITY OF FLORIDA · PI ANTON, STEPHEN D · 2009 to 2013
$575k
NCCIH NIH HHS K23 AT004251NCRR NIH HHS M01 RR002635NCRR NIH HHS RR-02635NHLBI NIH HHS HL073286NHLBI NIH HHS U01 HL073286NIA NIH HHS P30 AG028740NIDDK NIH HHS P30 DK072476PHS HHS K23 AY004251-01A2
6 · The paper itself

Abstract

Few well-controlled trials have evaluated the effects that macronutrient composition has on changes in food cravings during weight loss treatment. The present study, which was part of the Preventing Overweight Using Novel Dietary Strategies (POUNDS LOST) trial, investigated whether the fat and protein content of four different diets affected changes in specific food cravings in overweight and obese adults. A sample of 811 adults were recruited across two clinical sites, and each participant was randomly assigned to one of four macronutrient prescriptions: 1) low fat (20% of energy), average protein (15% of energy); 2) moderate fat (40%), average protein (15%); 3) low fat (20%), high protein (25%); 4) moderate fat (40%), high protein (25%). With few exceptions, the type of diet that participants were assigned did not differentially affect changes in specific food cravings. Participants assigned to the high-fat diets, however, had reduced cravings for carbohydrates at month 12 (p<0.05) and fruits and vegetables at month 24. Also, participants assigned to high-protein diets had increased cravings for sweets at month 6 and month 12 (ps<0.05). Participants in all four dietary conditions reported significant reductions in food cravings for specific types of foods (i.e., high fat foods, fast food fats, sweets, and carbohydrates/starches; all ps<0.05). Cravings for fruits and vegetables, however, were increased at month 24 (p<0.05). Calorically restricted diets (regardless of their macronutrient composition) yielded significant reductions in cravings for fats, sweets, and starches whereas cravings for fruits and vegetables were increased.

Indexed as

Caloric RestrictionDiet, ReducingFood PreferencesWeight LossAdultAgedAge FactorsBiomarkersBody Mass IndexDietary CarbohydratesDietary FatsDietary ProteinsFeeding BehaviorFemaleFollow-Up StudiesHumansBiomarkersDietary CarbohydratesDietary FatsDietary Proteins

Identifiers

PMID23010779
PMCPMC4189179
OpenAlexW2032965179

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.