Evidence map›Paper›PMID 23010228›Full record

ArticleAnnals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology2012

Effect of depressive symptoms on asthma intervention in urban teens.

Lokesh Guglani, Suzanne L Havstad, Christine Cole Johnson, Dennis R Ownby, Christine L M Joseph

Open access · greenAbstract read
In one paragraph

Article in Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Exploring the impact of elevated depressive symptoms on the ability of a tailored asthma intervention to improve medication adherence among urban adolescents with asthma.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Lokesh GuglaniPediatric Pulmonary Division, Department of Pediatrics, Children's Hospital of Michigan, Detroit, MI 48201, USA. lguglani@med.wayne.edu
Suzanne L Havstad
Christine Cole Johnson
Dennis R Ownby
Christine L M Joseph
Henry Ford Health System · USAugusta University Health · USChildren's Hospital of Michigan · US

Funding

Blood lead levels and development of asthmaR03HL067462 · NHLBI · HENRY FORD HEALTH SYSTEM · PI JOSEPH, CHRISTINE LM · 2001 to 2002
$137k
NHLBI NIH HHS R01 HL67462-01NHLBI NIH HHS R03 HL067462
6 · The paper itself

Abstract

backgroundThe literature suggests that depression is an important comorbidity in asthma that can significantly influence disease management and quality of life (QOL).

objectiveTo study the effect of coexisting depressive symptoms on the effectiveness of self-management interventions in urban teens with asthma.

methodsWe analyzed data from a randomized controlled trial of Puff City, a web-based, tailored asthma management intervention for urban teens, to determine whether depression modulated intervention effectiveness for asthma control and QOL outcomes. Teens and caregivers were classified as depressed based on responses collected from baseline questionnaires.

resultUsing logistic regression analysis, we found that a lower percentage of treatment students had indicators of uncontrolled asthma compared with controls (adjusted odds ratios <1). However, for teens depressed at baseline, QOL scores at follow-up were significantly higher in the treatment group compared with the control group for the emotions domain (adjusted relative risk, 2.08; 95% confidence interval, 1.2-3.63; P = .01; interpreted as emotional QOL for treatment students increased by a factor of 2.08 above controls). Estimates for overall QOL and symptoms QOL were borderline significant (adjusted relative risk, 1.57; 95% confidence interval, 0.93-2.63; P = .09; and adjusted relative risk, 1.72; 95% confidence interval, 0.94-3.15; P = .08; respectively). Among teens not depressed at baseline, no significant differences were observed between treatment and control groups in QOL domains at follow-up.

conclusionOur results suggest that depression modified the relationship between the effectiveness of an asthma intervention and emotional QOL in urban teens. Further assessment of self-management behavioral interventions for asthma should explore the mechanism by which depression may alter the intervention effect.

Indexed as

Adolescent BehaviorUrban HealthUrban PopulationAdolescentAsthmaBlack or African AmericanCaregiversChildDepressionFemaleHumansMaleMichiganRandomized Controlled Trials as TopicSurveys and Questionnaires

Identifiers

PMID23010228
PMCPMC4017370
OpenAlexW2022729763

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.