Evidence map›Paper›PMID 23009601›Full record

ArticleActa paediatrica (Oslo, Norway : 1992)2013

Markers for severity of illness associated with decreased snoring in toddlers born ELGA.

Katherine Wang, Juliann M Difiore, Richard J Martin, Carol L Rosen, Anna Maria Hibbs

Open access · greenAbstract read
In one paragraph

Article in Acta paediatrica (Oslo, Norway : 1992), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 82% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Katherine WangDepartment of Pediatrics, Rainbow Babies & Children's Hospital, Case Western Reserve University, Cleveland, OH 44106, USA. kwangstarks@gmail.com
Juliann M Difiore
Richard J Martin
Carol L Rosen
Anna Maria Hibbs
Case Western Reserve University · USRainbow Babies & Children's Hospital · US

Funding

NICHD Cooperative Multicenter Neonatal Research NetworkU10HD021364 · NICHD · CASE WESTERN RESERVE UNIVERSITY · PI WALSH, MICHELE · 1991 to 2015
$6.1M
Training in Neonatal ResearchT32HD060537 · NICHD · CASE WESTERN RESERVE UNIVERSITY · PI MARTIN, RICHARD JOHN · 2009 to 2018
$1.9M
Gastrointestinal Risk Factors for Wheezing in Premature InfantsK23HD056299 · NICHD · CASE WESTERN RESERVE UNIVERSITY · PI HIBBS, ANNA MARIA · 2007 to 2011
$651k
Intermittent Hypoxia and Retinopathy of prematurityR03HD064830 · NICHD · CASE WESTERN RESERVE UNIVERSITY · PI WILSON, CHRISTOPHER G · 2010 to 2011
$154k
NICHD NIH HHS 5R03HD064830-02NICHD NIH HHS 5T32HD060537-02NICHD NIH HHS 5U10HD021364-24NICHD NIH HHS K23 HD056299NICHD NIH HHS K23HD056299NICHD NIH HHS R03 HD064830NICHD NIH HHS T32 HD060537NICHD NIH HHS U10 HD021364
6 · The paper itself

Abstract

aimTo describe the prevalence of paediatric sleep disordered breathing (SDB) symptoms in extremely low gestational age infants and identify neonatal risk factors, including early exposure to hypoxia and hyperoxia.

methodsPatients <28 weeks gestation were monitored with high-resolution pulse oximetry. Hypoxia/hyperoxia variables were defined as percentage time of first 4 weeks of life that SaO(2) < 80% or SaO(2) > 98%, respectively. Parents completed part of the OSA-18 questionnaire for symptoms of SDB at 18-22 months. Logistic regression was used to test the association between risk factors and sleep symptoms.

resultsOf 182 patients recruited, 138 (76%) completed the questionnaire. The mean gestation was 26 weeks, and mean birth weight 887 grams. Loud snoring (21%) and restless sleep (24%) were the most prevalent symptoms. Female sex was associated with an increased risk of loud snoring (OR, 2.7; CI, 1.13-6.5). Prolonged mechanical ventilation, necrotizing enterocolitis and prolonged caffeine use, however, were inversely correlated with loud snoring. Neither neonatal hypoxia nor hyperoxia were associated with sleep symptoms.

conclusionsWhile the prevalence of sleep disordered breathing symptoms is similar to reported rates, we found a sex difference not previously reported. Interestingly, markers for severity of illness show a pattern of being protective against loud snoring.

Indexed as

Child, PreschoolFemaleGestational AgeHumansInfantInfant, NewbornInfant, PrematureInfant, Premature, DiseasesMalePrevalenceProspective StudiesRisk FactorsSeverity of Illness IndexSleep Apnea SyndromesSnoring

Identifiers

PMID23009601
PMCPMC3650629
OpenAlexW2143137891

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.