Trial reportBMC geriatrics2012
Study protocol: a randomised controlled trial of the effects of a multi-modal exercise program on cognition and physical functioning in older women.
Trial report in BMC geriatrics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Functional fitness benchmark values for older adults: a systematic review.Frontiers in public health · 2024Pooled it
- The influence of physical exercise and leisure activity on neuropsychological functioning in older adults.Age (Dordrecht, Netherlands) · 2015Trial
- Low-intensity daily walking activity is associated with hippocampal volume in older adults.Hippocampus · 2015Trial
- Chinese expert consensus on prevention and control interventions for older adults with physical functional impairment (2022).Aging medicine (Milton (N.S.W)) · 2023Article
- Balance Exercise Circuit for fall prevention in older adults: a randomized controlled crossover trial.Journal of frailty, sarcopenia and falls · 2022Article
- Relationships between cardiorespiratory fitness, hippocampal volume, and episodic memory in a population at risk for Alzheimer's disease.Brain and behavior · 2017Article
- The Effects of Exercise on the Physical Fitness of High and Moderate-Low Functioning Older Adult Women.Journal of aging research · 2016Article
- Study Protocol on Hormonal Mediation of Exercise on Cognition, Stress and Immunity (PRO-HMECSI): Effects of Different Exercise Programmes in Institutionalized Elders.Frontiers in public health · 2016Article
- Effects of non-pharmacological or pharmacological interventions on cognition and brain plasticity of aging individuals.Frontiers in systems neuroscience · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIntervention studies testing the efficacy of cardiorespiratory exercise have shown some promise in terms of improving cognitive function in later life. Recent developments suggest that a multi-modal exercise intervention that includes motor as well as physical training and requires sustained attention and concentration, may better elicit the actual potency of exercise to enhance cognitive performance. This study will test the effect of a multi-modal exercise program, for older women, on cognitive and physical functioning. METHODS/
designThis randomised controlled trial involves community dwelling women, without cognitive impairment, aged 65-75 years. Participants are randomised to exercise intervention or non-exercise control groups, for 16 weeks. The intervention consists of twice weekly, 60 minute, exercise classes incorporating aerobic, strength, balance, flexibility, co-ordination and agility training. Primary outcomes are measures of cognitive function and secondary outcomes include physical functioning and a neurocognitive biomarker (brain derived neurotrophic factor). Measures are taken at baseline and 16 weeks later and qualitative data related to the experience and acceptability of the program are collected from a sub-sample of the intervention group. DISCUSSION: If this randomised controlled trial demonstrates that multimodal exercise (that includes motor fitness training) can improve cognitive performance in later life, the benefits will be two-fold. First, an inexpensive, effective strategy will have been developed that could ameliorate the increased prevalence of age-related cognitive impairment predicted to accompany population ageing. Second, more robust evidence will have been provided about the mechanisms that link exercise to cognitive improvement allowing future research to be better focused and potentially more productive.
trial registrationAustralian and New Zealand Clinical Trial Registration Number: ANZCTR12612000451808.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.