ReviewDeutsches Arzteblatt international2012
Euthyroid goiter with and without nodules--diagnosis and treatment.
Review in Deutsches Arzteblatt international, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 36 citations in OpenAlex.
- Beyond the Thyroid: A Narrative Review of Extra-thyroidal Manifestations in Hashimoto's Disease.Cureus · 2024Review
- Emerging therapeutic role ofChinese herbal medicines · 2022Review
- Alteration of Trace Elements in Multinodular Goiter, Thyroid Adenoma, and Thyroid Cancer.Biological trace element research · 2021Article
- [Genetics of thyroid nodules and thyroid carcinoma].Der Internist · 2018Review
- Indications for the Surgical Management of Benign Goiter in Adults.Deutsches Arzteblatt international · 2018Review
- Fine Needle Aspiration in the Investigation of Thyroid Nodules.Deutsches Arzteblatt international · 2016Review
- Colchicum autumnale in Patients with Goitre with Euthyroidism or Mild Hyperthyroidism: Indications for a Therapeutic Regulative Effect-Results of an Observational Study.Evidence-based complementary and alternative medicine : eCAM · 2016Article
- [Clinical importance of thyroid gland cytology].Der Pathologe · 2015Review
- An Epidemiological Study of Risk Factors of Thyroid Nodule and Goiter in Chinese Women.International journal of environmental research and public health · 2015Article
- [Medullary thyroid carcinoma].Der Internist · 2015Article
- [Differentiated thyroid cancer].Der Internist · 2015Review
- Correspondence (letter to the editor): Ultrasound-guided percutaneous ethanol injection was not mentioned.Deutsches Arzteblatt international · 2013Article
- Correspondence (letter to the editor): Questions remain unanswered.Deutsches Arzteblatt international · 2013Article
- Correspondence (letter to the editor): Extremely low numbers of cases.Deutsches Arzteblatt international · 2013Article
- Correspondence (letter to the editor): Relevance of prevalence values.Deutsches Arzteblatt international · 2013Article
- Correspondence (letter to the editor): A big challenge.Deutsches Arzteblatt international · 2013Article
- Correspondence (letter to the editor): Poor sensitivity and specificity.Deutsches Arzteblatt international · 2013Article
- Correspondence (reply): In Reply.Deutsches Arzteblatt international · 2013Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThyroid enlargement and thyroid nodules are common in the general population. This review concerns their proper diagnostic assessment and treatment.
methodsWe selectively reviewed the literature from 1990 to 2012 and evaluated original articles and reviews retrieved from the PubMed database, as well as the recommendations of the following specialty societies: the German Societies of Endocrinology and Nuclear Medicine (Deutsche Gesellschaft für Endokrinologie, Deutsche Gesellschaft für Nuklearmedizin), the German Working Group for Endocrine Surgery (Chirurgische Arbeitsgemeinschaft Endokrinologie, CAEK), the European Thyroid Association, and the American Thyroid Association.
resultsThere have been very few randomized trials concerning the diagnosis and treatment of goiter. Nodular goiter can be managed by watchful waiting, drug treatment (initially with levothyroxine and iodide), radioactive iodine therapy, or surgery.
conclusionMany patients with nodules need no treatment at all. Treatment is indicated, however, if the patient is symptomatic and/or has an autonomously functioning ("hot") nodule, or if cancer is suspected. Potentially cancerous nodules must be operated on. If euthyroid nodular goiter is to be treated with the main goal of size reduction, either surgery or radioactive iodine therapy can be used. Drug treatment is an option for small nodules or goiters, but iatrogenic hyperthyroidism must be avoided at all costs. The type of follow-up that is required depends on the chosen treatment.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.