Evidence map›Paper›PMID 23008276›Full record

ArticleEnvironmental health perspectives2012

Rice consumption and urinary arsenic concentrations in U.S. children.

Matthew A Davis, Todd A Mackenzie, Kathryn L Cottingham, Diane Gilbert-Diamond, Tracy Punshon, Margaret R Karagas

Abstract read
In one paragraph

Article in Environmental health perspectives, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
81citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

81 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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  13. A State-of-the-Science Review on Metal Biomarkers.Current environmental health reports · 2023
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21 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Matthew A DavisInstitute for Quantitative Biomedical Sciences, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire 03756, USA.
Todd A Mackenzie
Kathryn L Cottingham
Diane Gilbert-Diamond
Tracy Punshon
Margaret R Karagas

Funding

Translational Engineering in Cancer (TEC)P30CA023108 · NCI · DARTMOUTH COLLEGE · PI Steven D Leach · 1985 to 2026
$91.3M
VARIATION IN BIOACCUMULATION AND BIOMAGNIFICATION OF METALS IN NORTHERN US LAKESP42ES007373 · NIEHS · DARTMOUTH COLLEGE · PI STANTON, BRUCE A. · 1995 to 2019
$52.0M
Training Program for Quantitative Population Sciences in CancerR25CA134286 · NCI · DARTMOUTH COLLEGE · PI KARAGAS, MARGARET RITA, TOSTESON, TOR D · 2009 to 2018
$3.0M
Project 4: Determining How Arsenic Modulates Hedgehog Signaling During DevelopmenP20ES018175 · NIEHS · DARTMOUTH COLLEGE · PI KARAGAS, MARGARET RITA · 2010 to 2012
$892k
The United States Complementary and Alternative Medicine MarketK01AT006162 · NCCIH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DAVIS, MATTHEW A · 2010 to 2014
$706k
NCCIH NIH HHS K01 AT006162NCCIH NIH HHS K01AT006162NCI NIH HHS P30 CA023108NCI NIH HHS R25 CA134286NCI NIH HHS R25CA134286NIEHS NIH HHS P20 ES018175NIEHS NIH HHS P42 ES007373
6 · The paper itself

Abstract

backgroundIn adult populations, emerging evidence indicates that humans are exposed to arsenic by ingestion of contaminated foods such as rice, grains, and juice; yet little is known about arsenic exposure among children.

objectivesOur goal was to determine whether rice consumption contributes to arsenic exposure in U.S. children.

methodsWe used data from the nationally representative National Health and Nutrition Examination Survey (NHANES) to examine the relationship between rice consumption (measured in 0.25 cups of cooked rice per day) over a 24-hr period and subsequent urinary arsenic concentration among the 2,323 children (6-17 years of age) who participated in NHANES from 2003 to 2008. We examined total urinary arsenic (excluding arsenobetaine and arsenocholine) and dimethylarsinic acid (DMA) concentrations overall and by age group: 6-11 years and 12-17 years.

resultsThe median [interquartile range (IQR)] total urinary arsenic concentration among children who reported consuming rice was 8.9 μg/L (IQR: 5.3-15.6) compared with 5.5 μg/L (IQR: 3.1-8.4) among those who did not consume rice. After adjusting for potentially confounding factors, and restricting the study to participants who did not consume seafood in the preceding 24 hr, total urinary arsenic concentration increased 14.2% (95% confidence interval: 11.3, 17.1%) with each 0.25 cup increase in cooked rice consumption.

conclusionsOur study suggests that rice consumption is a potential source of arsenic exposure in U.S. children.

Indexed as

Environmental ExposureOryzaAdolescentArsenicCacodylic AcidChildChromatography, High Pressure LiquidEnvironmental MonitoringFood ContaminationHumansLinear ModelsMass SpectrometryNutrition SurveysUnited StatesArsenicCacodylic Acid

Identifiers

PMID23008276
PMCPMC3491944

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.