ArticleEnvironmental health perspectives2012
Airborne PM2.5 chemical components and low birth weight in the northeastern and mid-Atlantic regions of the United States.
Article in Environmental health perspectives, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02786420 (Imaging Innovations for Placental Assessment in Response to Environmental Pollution), which is not on this map. Cited by 81 papers, 4 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Imaging Innovations for Placental Assessment in Response to Environmental Pollution
Who cites it
81 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Gestational age modifies the association between exposure to fine particles and fetal death: findings from a nationwide epidemiological study in the contiguous United States.Environmental health : a global access science source · 2023Pooled it
- Maternal fine particulate matter (PMEnvironmental science and pollution research international · 2019Pooled it
- Maternal exposure to fine particulate matter (PM2.5) and pregnancy outcomes: a meta-analysis.Environmental science and pollution research international · 2015Pooled it
- A systematic review of the physical health impacts from non-occupational exposure to wildfire smoke.Environmental research · 2015Pooled it
- Temporal Variation in the Association Between Short-term Exposure to Fine Particulate Matter and Mortality Across Subpopulations in North Carolina and Michigan, U.S.Epidemiology (Cambridge, Mass.) · 2026Article
- Windows of susceptibility to fine particulate matter components for fetal birth weight: a birth cohort study.BMC public health · 2026Article
- Traffic-Related Air Pollution and Birth Weight: The Roles of Noise, Placental Function, Green Space, Physical Activity, and Socioeconomic Status (FRONTIER).Research report (Health Effects Institute) · 2026Article
- Air Pollution Exposure and Birth Weight in the ECHO Cohort.JAMA network open · 2025Article
- Clustering environmental pollutants associated with increased risk of metabolic disease: a hierarchical analysis.Health information science and systems · 2025Article
- Associations between satellite-derived estimates of PM2.5 species concentrations for organic carbon, elemental carbon, nitrate, and sulfate with birth weight and preterm birth in California during 2005-2014.Journal of exposure science & environmental epidemiology · 2025Article
- High-Resolution Estimation of Daily PMRemote sensing · 2025Article
- Interpregnancy interval, air pollution, and the risk of low birth weight: a retrospective study in China.BMC public health · 2024Article
- Inhalation of particulate matter containing environmentally persistent free radicals induces endothelial dysfunction mediated via AhR activation at the air-blood interface.Toxicological sciences : an official journal of the Society of Toxicology · 2024Article
- Prenatal exposure to air pollutant mixtures and birthweight in the upstate KIDS cohort.Environment international · 2024Article
- Prenatal exposure to air pollution and BWGA Z-score: Modifying effects of placenta leukocyte telomere length and infant sex.Environmental research · 2024Article
- Health Impacts of Future Prescribed Fire Smoke: Considerations From an Exposure Scenario in California.Earth's future · 2024Article
- Effects of in-utero personal exposure to PMScientific reports · 2023Article
- Maternal exposure to ambient air pollution mixture and premature rupture of membranes: Evidence from a large cohort in Southern California (2008-2018).Environment international · 2023Article
- Effects of In-Utero Personal Exposure to PM2.5 Sources and Components on Birthweight.Research square · 2023Article
- A bibliometric analysis of the impact of COVID-19 social lockdowns on air quality: research trends and future directions.Environmental science and pollution research international · 2023Review
21 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
backgroundPrevious studies on air pollutants and birth outcomes have reported inconsistent results. Chemical components of particulate matter ≤ 2.5 µm (PM2.5) composition are spatially -heterogeneous, which might contribute to discrepancies across PM2.5 studies.
objectivesWe explored whether birth weight at term is affected by PM2.5, PM10 (PM ≤ 10 µm), and gaseous pollutants.
methodsWe calculated exposures during gestation and each trimester for PM2.5 chemical components, PM10, PM2.5, carbon monoxide, nitrogen dioxide, ozone, and sulfur dioxide for births in 2000-2007 for states in the northeastern and mid-Atlantic United States. Associations between exposures and risk of low birth weight (LBW) were adjusted by family and individual characteristics and region. Interaction terms were used to investigate whether risk differs by race or sex.
resultsSeveral PM2.5 chemical components were associated with LBW. Risk increased 4.9% (95% CI: 3.4, 6.5%), 4.7% (3.2, 6.2%), 5.7% (2.7, 8.8%), and 5.0% (3.1, 7.0%) per interquartile range increase of PM2.5 aluminum, elemental carbon, nickel, and titanium, respectively. Other PM2.5 chemical components and gaseous pollutants showed associations, but were not statistically significant in multipollutant models. The trimester associated with the highest relative risk differed among pollutants. Effect estimates for PM2.5 elemental carbon and nickel were higher for infants of white mothers than for those of African-American mothers, and for males than females.
conclusionsMost exposure levels in our study area were in compliance with U.S. Environmental Protection Agency air pollution standards; however, we identified associations between PM2.5 components and LBW. Findings suggest that some PM2.5 components may be more harmful than others, and that some groups may be particularly susceptible.
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