ReviewNature reviews. Rheumatology2012
Emerging optical and nuclear medicine imaging methods in rheumatoid arthritis.
Review in Nature reviews. Rheumatology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 57 citations in OpenAlex.
- Total-body positron emission tomography: a tool for systemic, quantitative evaluation of the inflammatory burden of psoriatic arthritis.Rheumatology (Oxford, England) · 2025Article
- EXPLORing Arthritis with Total-body Positron Emission Tomography.Seminars in musculoskeletal radiology · 2023Review
- Activatable fluorescent probes for imaging and diagnosis of rheumatoid arthritis.Military Medical Research · 2023Review
- Peptide Self-Assembled Nanocarriers for Cancer Drug Delivery.The journal of physical chemistry. B · 2023Review
- Feasibility of dual-phaseQuantitative imaging in medicine and surgery · 2021Article
- Total-Body PET Imaging of Musculoskeletal Disorders.PET clinics · 2021Review
- Comparison of the Heel Enthesitis MRI Scoring System (HEMRIS) with clinical enthesitis and local metabolic activity on PET-CT.RMD open · 2020Observational
- Evaluation of the therapeutic potential of the selective p38 MAPK inhibitor Skepinone-L and the dual p38/JNK 3 inhibitor LN 950 in experimental K/BxN serum transfer arthritis.Inflammopharmacology · 2019Article
- Light-Addressable Nanoclusters of Ultrasmall Iron Oxide Nanoparticles for Enhanced and Dynamic Magnetic Resonance Imaging of Arthritis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2019Article
- A Mobile App With Optical Imaging for the Self-Management of Hand Rheumatoid Arthritis: Pilot Study.JMIR mHealth and uHealth · 2018Article
- Synovitis in mice with inflammatory arthritis monitored with quantitative analysis of dynamic contrast-enhanced NIR fluorescence imaging using iRGD-targeted liposomes as fluorescence probes.International journal of nanomedicine · 2018Article
- Detection of Subclinical Arthritis in Mice by a Thrombin Receptor-Derived Imaging Agent.Arthritis & rheumatology (Hoboken, N.J.) · 2018Article
- Editorial: Ratiometric Optical Imaging of Subclinical Inflammation With a Thrombin-Cleavable Probe: A Future Tool for the In Vivo Visualization of Clinically Silent Synovitis?Arthritis & rheumatology (Hoboken, N.J.) · 2018Article
- In-vivo quantitative assessment of the therapeutic response in a mouse model of collagen-induced arthritis usingClinical and experimental immunology · 2017Article
- Development of the Digital Arthritis Index, a Novel Metric to Measure Disease Parameters in a Rat Model of Rheumatoid Arthritis.Frontiers in pharmacology · 2017Article
- Rheumatoid Arthritis Revisited - Advanced Imaging Review.Polish journal of radiology · 2016Review
- Noninvasive Imaging of Nanomedicines and Nanotheranostics: Principles, Progress, and Prospects.Chemical reviews · 2015Review
- The influence of polysorbate 80 on the radiochemical synthesis of a PET tracer in the FASTlab.Pharmaceutical research · 2015Article
- Alarmin S100A8/S100A9 as a biomarker for molecular imaging of local inflammatory activity.Nature communications · 2014Article
- Molecular imaging of rheumatoid arthritis: emerging markers, tools, and techniques.Arthritis research & therapy · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
Abstract
Molecular and multimodal imaging procedures that complement the use of existing anatomical modalities for the diagnosis and monitoring of rheumatoid arthritis (RA) have undergone substantial developmental advances. These techniques have the potential to greatly improve the management of patients with RA through early diagnosis and maximization of the newly available opportunities for early therapeutic intervention. Quantitative, noninvasive monitoring of biomarkers of the molecular events induced during the onset of RA could be used to guide the initial selection of therapy and for assessment of early therapeutic responses. Biomolecular imaging techniques that can reveal the pathophysiological features of RA--including infrared thermography, near-infrared molecular imaging, and PET--are being used to investigate the earliest cellular and biochemical inflammatory events in the development of the disease. Noninvasive imaging of abnormal specific molecular events in early RA could enable early targeted intervention that could be tailored to optimize patient responses before destructive anatomical changes occur. In this Review, we summarize new advances in biomolecular imaging techniques, with an emphasis on their current state of development in terms of the management of RA.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.