ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2013
Epidemiology of stroke in northern Italy: the Cerebrovascular Aosta Registry, 2004-2008.
Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 6 of them syntheses that pooled it.
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15 citing papers in PubMed, 6 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- Case fatality and functional outcome after spontaneous subarachnoid haemorrhage: A systematic review and meta-analysis of time trends and regional variations in population-based studies.European stroke journal · 2024Pooled it
- Diverging Temporal Trends in Stroke Incidence in Younger vs Older People: A Systematic Review and Meta-analysis.JAMA neurology · 2022Pooled it
- [Prevalence and incidence of ictus in Europe: systematic review and meta-analysis].Anales del sistema sanitario de Navarra · 2022Pooled it
- Pooled it
- Worldwide Incidence of Aneurysmal Subarachnoid Hemorrhage According to Region, Time Period, Blood Pressure, and Smoking Prevalence in the Population: A Systematic Review and Meta-analysis.JAMA neurology · 2019Pooled it
- The association of telomere attrition with first-onset stroke in Southern Chinese: a case-control study and meta-analysis.Scientific reports · 2018Pooled it
- Article
- Incidence, case fatality, and functional outcome of intracerebral haemorrhage, according to age, sex, and country income level: a systematic review and meta-analysis.The Lancet regional health. Europe · 2025Article
- Case Fatality of Aneurysmal Subarachnoid Hemorrhage Varies by Geographic Region Within Finland: A Nationwide Register-Based Study.Neurology · 2023Article
- Acupuncture combined with moxibustion for insomnia after stroke: A protocol for systematic review and meta analysis.Medicine · 2021Article
- Poor self-rated health predicts the incidence of functional disability in elderly community dwellers in Japan: a prospective cohort study.BMC geriatrics · 2020Article
- Stroke Incidence in Victoria, Australia-Emerging Improvements.Frontiers in neurology · 2017Article
- Hospital-based register of stroke in the Molise Region: focus on main subtypes of stroke. Years 2009-2013.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2016Article
- Outcome Predictors in First-Ever Ischemic Stroke Patients: A Population-Based Study.International scholarly research notices · 2014Article
- Blocking neurogenic inflammation for the treatment of acute disorders of the central nervous system.International journal of inflammation · 2013Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Our aim was to prospectively ascertain the incidence of first-ever stroke and ischaemic stroke subtypes, mortality, functional outcome and recurrence in northern Italy. We identified all possible cases of stroke (1st January 2004 and 31st December 2008). Multiple overlapping sources were used. Standard definitions for incident cases, pathological types and infarction subtypes were used. Patient characteristics were identified and analysed, case-fatality was ascertained from administrative databases, and outcome was assessed in all surviving patients by modified Rankin Scale. We identified 1,326 incident strokes. The pathological diagnosis was confirmed in 94% of cases. The incidence of first-ever stroke was 80.2 per 100,000 (95% CI 73-87) when adjusted to world population. The incidence of embolic stroke was significantly greater in women than in men (p < 0.001) whereas the incidence of atherothrombotic stroke was significantly greater in men than in women (p < 0.001). The case-fatality of incident strokes was 9.5% at 7 day, 16.1% at 28 day, and 29.9% at 1 year. Case-fatality of ischaemic stroke was lower than that of other pathological types (p < 0.0001). Hypertension was the most important risk factor, and atrial fibrillation was the most common in embolic stroke. Increasing age, female gender and embolic stroke subtypes were associated with an adverse outcome. Data on stroke incidence and case-fatality were similar to those of other high-income countries. However, differences were found in the distribution of risk factors and prognosis across the stroke types and ischaemic stroke subtypes. Gender differences in long-term functional outcomes were significant.
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