ArticleActa veterinaria Scandinavica2012
Applicability of major histocompatibility complex DRB1 alleles as markers to detect vertebrate hybridization: a case study from Iberian ibex × domestic goat in southern Spain.
Article in Acta veterinaria Scandinavica, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 22 citations in OpenAlex.
- Hybridization between Alpine Ibex and Domestic Goat in the Alps: A Sporadic and Localized Phenomenon?Animals : an open access journal from MDPI · 2022Article
- Genetic signature of blind reintroductions of Iberian ibex (Capra pyrenaica) in Catalonia, Northeast Spain.PloS one · 2022Article
- Assessing the levels of intraspecific admixture and interspecific hybridization in Iberian wild goats (Evolutionary applications · 2021Article
- Heterozygosity-fitness correlation at the major histocompatibility complex despite low variation in Alpine ibex (Evolutionary applications · 2018Article
- Hidden MHC genetic diversity in the Iberian ibex (Capra pyrenaica).BMC genetics · 2018Article
- A review of Sarcoptes scabiei: past, present and future.Parasites & vectors · 2017Review
- Association of SNP variants of MHC Class II DRB gene with thermo-physiological traits in tropical goats.Tropical animal health and production · 2017Article
- First evidence of hybridization between golden jackal (Canis aureus) and domestic dog (Canis familiaris) as revealed by genetic markers.Royal Society open science · 2015Article
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHybridization between closely related wild and domestic species is of great concern because it can alter the evolutionary integrity of the affected populations. The high allelic variability of Major Histocompatibility Complex (MHC) loci usually excludes them from being used in studies to detect hybridization events. However, if a) the parental species don't share alleles, and b) one of the parental species possesses an exceptionally low number of alleles (to facilitate analysis), then even MHC loci have the potential to detect hybrids.
resultsBy genotyping the exon2 of the MHC class II DRB1 locus, we were able to detect hybridization between domestic goats (Capra hircus) and free-ranging Iberian ibex (Capra pyrenaica hispanica) by molecular means.
conclusionsThis is the first documentation of a Capra pyrenaica × Capra hircus hybridization, which presented us the opportunity to test the applicability of MHC loci as new, simple, cost-effective, and time-saving approach to detect hybridization between wild species and their domesticated relatives, thus adding value to MHC genes role in animal conservation and management.
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