ArticleProceedings of the National Academy of Sciences of the United States of America1990
Transcription and cap trimethylation of a nematode spliced leader RNA in a cell-free system.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1990. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 42 citations in OpenAlex.
- 5'-Terminal chemical capping of spliced leader RNAs.Tetrahedron letters · 2012Article
- Synthesis of ¹³C- and ¹⁴C-labeled dinucleotide mRNA cap analogues for structural and biochemical studies.Bioorganic & medicinal chemistry letters · 2012Article
- The nematode eukaryotic translation initiation factor 4E/G complex works with a trans-spliced leader stem-loop to enable efficient translation of trimethylguanosine-capped RNAs.Molecular and cellular biology · 2010Article
- Structural insights into parasite eIF4E binding specificity for m7G and m2,2,7G mRNA caps.The Journal of biological chemistry · 2009Article
- Spliced leader trans-splicing in the nematode Trichinella spiralis uses highly polymorphic, noncanonical spliced leaders.RNA (New York, N.Y.) · 2008Article
- In vivo translation and stability of trans-spliced mRNAs in nematode embryos.Molecular and biochemical parasitology · 2007Article
- Article
- Dcp2 Decaps m2,2,7GpppN-capped RNAs, and its activity is sequence and context dependent.Molecular and cellular biology · 2005Article
- Exploring nematode diversity.Nature genetics · 2004Article
- Nematode m7GpppG and m3(2,2,7)GpppG decapping: activities in Ascaris embryos and characterization of C. elegans scavenger DcpS.RNA (New York, N.Y.) · 2004Article
- Characterization of human RNA polymerase III identifies orthologues for Saccharomyces cerevisiae RNA polymerase III subunits.Molecular and cellular biology · 2002Article
- Redundant cooperative interactions for assembly of a human U6 transcription initiation complex.Molecular and cellular biology · 2002Article
- Developmentally regulated telomerase activity is correlated with chromosomal healing during chromatin diminution in Ascaris suum.Molecular and cellular biology · 1999Article
- In vivo function of mutated spliced leader RNAs in Caenorhabditis elegans.Proceedings of the National Academy of Sciences of the United States of America · 1998Article
- The large subunit of basal transcription factor SNAPc is a Myb domain protein that interacts with Oct-1.Molecular and cellular biology · 1998Article
- The largest subunit of human RNA polymerase III is closely related to the largest subunit of yeast and trypanosome RNA polymerase III.Genome research · 1997Article
- Orphon spliced-leader sequences form part of a repetitive element in Angiostrongylus cantonensis.Nucleic acids research · 1995Article
- mRNA processing in the Trypanosomatidae.Experientia · 1991Review
- Accurate and efficient RNA polymerase II transcription with a soluble nuclear fraction derived from Drosophila embryos.Proceedings of the National Academy of Sciences of the United States of America · 1991Article
- Mutant Caenorhabditis elegans RNA polymerase II with a 20,000-fold reduced sensitivity to alpha-amanitin.Genetics · 1990Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Maturation of a fraction of mRNAs in nematodes involves the acquisition of a common 5' terminal spliced leader sequence derived from a nonpolyadenylylated spliced leader RNA by trans splicing. We have developed a cell-free system prepared from Ascaris lumbricoides embryos that accurately and efficiently synthesized the spliced leader RNA of A. lumbricoides. Transcription of the spliced leader RNA was catalyzed by RNA polymerase II, and the majority of the spliced leader RNAs synthesized in vitro possessed a trimethylguanosine cap structure identical to that found on in vivo-synthesized spliced leader RNA.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.