ReviewCurrent hypertension reports2012
Striking a balance: autophagy, apoptosis, and necrosis in a normal and failing heart.
Review in Current hypertension reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed.
- Mechanism of new optimized Sheng-Mai-San Formula to regulate cardiomyocyte apoptosis through NMDAR pathway.Heliyon · 2023Article
- Circ-GTF2I/miR-590-5p Axis Aggravates Myocardial Ischemia-Reperfusion Injury by Regulating Kelch Repeat and BTB Domain-Containing Protein 7.Evidence-based complementary and alternative medicine : eCAM · 2022Article
- PM2.5-related cell death patterns.International journal of medical sciences · 2021Review
- Mitochondrial Dysfunction in Diabetic Cardiomyopathy: The Possible Therapeutic Roles of Phenolic Acids.International journal of molecular sciences · 2020Review
- Dexmedetomidine alleviated sepsis‑induced myocardial ferroptosis and septic heart injury.Molecular medicine reports · 2020Article
- Ginkgolide B inhibits hydrogen peroxide‑induced apoptosis and attenuates cytotoxicity via activating the PI3K/Akt/mTOR signaling pathway in H9c2 cells.Molecular medicine reports · 2020Article
- Implications of Necroptosis for Cardiovascular Diseases.Current medical science · 2019Review
- Loading necrostatin-1 composite bone cement inhibits necroptosis of bone tissue in rabbit.Regenerative biomaterials · 2019Article
- Bucindolol Modulates Cardiac Remodeling by Attenuating Oxidative Stress in H9c2 Cardiac Cells Exposed to Norepinephrine.Oxidative medicine and cellular longevity · 2019Article
- 68Ga-Galmydar: A PET imaging tracer for noninvasive detection of Doxorubicin-induced cardiotoxicity.PloS one · 2019Article
- MicroRNA 199a-5p induces apoptosis by targeting JunB.Scientific reports · 2018Article
- Hydrogen Sulfide Regulating Myocardial Structure and Function by Targeting Cardiomyocyte Autophagy.Chinese medical journal · 2018Review
- The spectrum of myocardial homeostasis mechanisms in the settings of cardiac surgery procedures (Review).Molecular medicine reports · 2018Review
- Autophagy inhibitor 3-methyladenine alleviates overload-exercise-induced cardiac injury in rats.Acta pharmacologica Sinica · 2017Article
- Glycyrrhetinic acid protects H9c2 cells from oxygen glucose deprivation-induced injury through the PI3K/AKt signaling pathway.Journal of natural medicines · 2017Article
- The role of autophagy in cardiac hypertrophy.Acta biochimica et biophysica Sinica · 2016Review
- Mitochondrial involvement in myocyte death and heart failure.Heart failure reviews · 2016Review
- Targeted deletion of PTEN in cardiomyocytes renders cardiac contractile dysfunction through interruption of Pink1-AMPK signaling and autophagy.Biochimica et biophysica acta · 2015Article
- Bnip3 mediates doxorubicin-induced cardiac myocyte necrosis and mortality through changes in mitochondrial signaling.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- Lysine methyltransferase Smyd2 suppresses p53-dependent cardiomyocyte apoptosis.Biochimica et biophysica acta · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Despite the progress that has been made over the past two decades in cardiovascular research, heart failure remains a major cause of morbidity and mortality worldwide. Insight into the cellular and molecular mechanisms that underlie the heart failure in individuals with ischemic heart disease have identified defects in cellular processes that govern autophagy, apoptosis and necrosis as a prevailing underlying cause. Indeed, programmed cell death of cardiac cells by apoptosis or necrosis is believed to involve the intrinsic mitochondrial pathway and/or extrinsic death receptor pathway by certain Bcl-2 family members as well as components of the TNFα signaling pathway. In this review, we discuss recent advances in the molecular signaling factors that govern cardiac cell fate under normal and disease conditions.
Indexed as
Identifiers
23001875What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.