Evidence map›Paper›PMID 23001745›Full record

SynthesisCurrent atherosclerosis reports2012

Unprocessed red and processed meats and risk of coronary artery disease and type 2 diabetes--an updated review of the evidence.

Renata Micha, Georgios Michas, Dariush Mozaffarian

Registry-linked trialAbstract readMeta-AnalysisReview
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Current atherosclerosis reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06157385 (The Effect of Culinary Medicine to Enhance Protein Intake on Muscle Quality in Older Adults), which is not on this map. Cited by 214 papers, 22 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
214citing papers in PubMed, 22 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06157385 nacompletednot on this mapstarted 2023, after this paper: background citation

The Effect of Culinary Medicine to Enhance Protein Intake on Muscle Quality in Older Adults

TypeinterventionalSponsorTexas Tech UniversityRan2023 to 2024Enrolled28ConditionsSarcopeniaArmsCulinary Medicine, Control
3 · Its place in the literature

Who cites it

214 citing papers in PubMed, 22 syntheses or guidelines pooled it.

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154 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Renata MichaDepartment of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA.
Georgios Michas
Dariush Mozaffarian

Funding

Determinants and Cardiovascular Consequences of Diabetes in Older AdultsR01HL094555 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI ARNOLD, ALICE A., DJOUSSE, LUC · 2009 to 2012
$5.9M
NHLBI NIH HHS R01 HL094555
6 · The paper itself

Abstract

Growing evidence suggests that effects of red meat consumption on coronary heart disease (CHD) and type 2 diabetes could vary depending on processing. We reviewed the evidence for effects of unprocessed (fresh/frozen) red and processed (using sodium/other preservatives) meat consumption on CHD and diabetes. In meta-analyses of prospective cohorts, higher risk of CHD is seen with processed meat consumption (RR per 50 g: 1.42, 95 %CI = 1.07-1.89), but a smaller increase or no risk is seen with unprocessed meat consumption. Differences in sodium content (~400 % higher in processed meat) appear to account for about two-thirds of this risk difference. In similar analyses, both unprocessed red and processed meat consumption are associated with incident diabetes, with higher risk per g of processed (RR per 50 g: 1.51, 95 %CI = 1.25-1.83) versus unprocessed (RR per 100 g: 1.19, 95 % CI = 1.04-1.37) meats. Contents of heme iron and dietary cholesterol may partly account for these associations. The overall findings suggest that neither unprocessed red nor processed meat consumption is beneficial for cardiometabolic health, and that clinical and public health guidance should especially prioritize reducing processed meat consumption.

Indexed as

Coronary Artery DiseaseDiabetes Mellitus, Type 2DietHumansMeat ProductsProspective StudiesRisk

Identifiers

PMID23001745
PMCPMC3483430

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.