Evidence map›Paper›PMID 23001641›Full record

ArticleInternational urology and nephrology2013

Can mycoplasma contribute to formation of prostate cancer?

Sakip M Erturhan, Omer Bayrak, Sacide Pehlivan, Hanifi Ozgul, Ilker Seckiner, Tugce Sever, Metin Karakök

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In one paragraph

Article in International urology and nephrology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. Heliyon · 2023
    Article
  4. Multiple pathogens and prostate cancer.Infectious agents and cancer · 2022
    Review
  5. Pathogens (Basel, Switzerland) · 2021
    Article
  6. Article
  7. The Relationship betweenJournal of oncology · 2021
    Review
  8. Article
  9. Classification of non-gonococcal urethritis: a review.International urology and nephrology · 2019
    Review
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sakip M ErturhanDepartment of Urology, School of Medicine, University of Gaziantep, 27310 Gaziantep, Turkey.
Omer Bayrak
Sacide Pehlivan
Hanifi Ozgul
Ilker Seckiner
Tugce Sever
Metin Karakök

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo reveal the possible role of mycoplasmas in the etiopathogenesis of prostate cancer.

methodsIn the study, prostate biopsy was performed on 62 patients with an abnormal digital rectal examination and/or elevated PSA. The patients' age was between 62 and 77 (mean 65.4 years) years. Thirty-one patients had adenocarcinoma of the prostate histopathologically (group 1). From these patients, the specimens were divided into two subgroups as specimens with malignant findings (group 1A) and specimens with benign findings (group 1B). The control group consisted of 31 patients with benign prostatic hyperplasia (group 2). In the specimens, the presence of mycoplasma DNA was investigated by the polymerase chain reaction method.

resultsThe mycoplasma DNA was found to be positive in 11 (35.4 %) patients in group 1A and in 4 (12.9 %) patients in group 1B. There was no mycoplasma DNA in the patients in group 2. The differences between group 1A and group 1B, and between group 1A and group 2 were statistically significant (p values, respectively, 0.006 and 0.0001).

conclusionsOur data supported the thesis that mycoplasma infections play a role in the etiopathogenesis of the prostate cancer.

Indexed as

AdenocarcinomaAgedDigital Rectal ExaminationDNA, BacterialHumansMaleMiddle AgedMycoplasmaMycoplasma InfectionsProstateProstate-Specific AntigenProstatic HyperplasiaProstatic NeoplasmsDNA, BacterialProstate-Specific Antigen

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.