Evidence map›Paper›PMID 23001157›Full record

ArticleThe international journal of cardiovascular imaging2013

Aortic stiffness is related to left ventricular diastolic function in patients with diabetes mellitus type 1: assessment with MRI and speckle tracking strain analysis.

Linda D van Schinkel, Dominique Auger, Saskia G C van Elderen, Nina Ajmone Marsan, Victoria Delgado, Hildo J Lamb, Arnold C T Ng, Johannes W A Smit, Jeroen J Bax, Jos J M Westenberg and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in The international journal of cardiovascular imaging, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Arterial Thickness and Stiffness Are Independently Associated with Left Ventricular Strain.Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography · 2018
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Cardiovascular imaging 2013 in the International Journal of Cardiovascular Imaging.The international journal of cardiovascular imaging · 2014
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Linda D van SchinkelDepartment of Endocrinology, Leiden University Medical Center, Albinusdreef 2, C4-67, 2333 ZA Leiden, The Netherlands. l.d.van_schinkel@lumc.nl
Dominique Auger
Saskia G C van Elderen
Nina Ajmone Marsan
Victoria Delgado
Hildo J Lamb
Arnold C T Ng
Johannes W A Smit
Jeroen J Bax
Jos J M Westenberg
Albert de Roos
Leiden University Medical Center · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetes mellitus type 1 (DM1) is associated with aortic stiffening and left ventricular (LV) diastolic dysfunction, however the relationship between aortic stiffness and LV diastolic dysfunction in DM1 patients is still largely unknown. The purpose of this study was to evaluate whether an increased aortic stiffness, expressed by increased aortic pulse wave velocity (PWV), is associated with subclinical LV diastolic dysfunction and decreased left atrial (LA) compliance as assessed with speckle tracking strain analysis in patients with DM1. Aortic PWV was assessed with cardiovascular magnetic resonance in 41 DM1 patients. Patients underwent echocardiography for assessment of conventional LV diastolic function indices and LV and LA longitudinal strain and strain rate (SR) assessed with speckle tracking strain analysis. LV SR during the isovolumic relaxation period (SRIVR) and LA strain were recorded and the E-wave velocity to SRIVR velocity ratio (E/SRIVR) was calculated. Independent samples t test and multivariate linear regression analyses were used for statistical analyses. Aortic PWV significantly correlated with SRIVR (β = -0.71, p < 0.001), E/SRIVR (β = 0.61, p = 0.002) and LA strain (β = -0.47, p = 0.014), but not with conventional echocardiographic markers of diastolic function (all p > 0.10). In DM1 patients, aortic stiffness is inversely associated with sensitive markers of LV diastolic function and decrease in LA compliance as measured with echocardiographic speckle tracking strain analysis.

Indexed as

Echocardiography, DopplerMagnetic Resonance ImagingMyocardial ContractionVascular StiffnessVentricular Function, LeftAdultAgedAtrial Function, LeftChi-Square DistributionComplianceCross-Sectional StudiesDiabetes Mellitus, Type 1FemaleHumansLinear ModelsMale

Identifiers

PMID23001157
OpenAlexW2092670948

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.