Evidence map›Paper›PMID 23000743›Full record

ReviewAdvanced drug delivery reviews2013

Perspectives on the interface of drug delivery and tissue engineering.

Adam K Ekenseair, F Kurtis Kasper, Antonios G Mikos

Abstract readReview
In one paragraph

Review in Advanced drug delivery reviews, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Refillable silicone pump with precise switching for timed therapeutic delivery.Frontiers in bioengineering and biotechnology · 2025
    Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Adam K EkenseairDepartment of Bioengineering, Rice University, Houston, TX 77030, USA.
F Kurtis Kasper
Antonios G Mikos

Funding

Injectable Cellular Composites for Cartilage EngineeringR01AR048756 · NIAMS · RICE UNIVERSITY · PI KASPER, FRED KURTIS, MIKOS, ANTONIOS G. · 2003 to 2014
$3.3M
In Situ Hardening Cellular Constructs for Craniofacial Bone RegenerationR01DE017441 · NIDCR · RICE UNIVERSITY · PI MIKOS, ANTONIOS G. · 2008 to 2012
$1.6M
Flow Perfusion Bioreactor Fabrication of Bioactive Polymer/ECM Hybrid ConstructsR01AR057083 · NIAMS · RICE UNIVERSITY · PI MIKOS, ANTONIOS G. · 2009 to 2013
$1.6M
NIAMS NIH HHS R01 AR048756NIAMS NIH HHS R01 AR057083NIDCR NIH HHS R01 DE017441
6 · The paper itself

Abstract

Controlled drug delivery of bioactive molecules continues to be an essential component of engineering strategies for tissue defect repair. This article surveys the current challenges associated with trying to regenerate complex tissues utilizing drug delivery and gives perspectives on the development of translational tissue engineering therapies which promote spatiotemporal cell-signaling cascades to maximize the rate and quality of repair.

Indexed as

Biological ProductsDrug Delivery SystemsHumansTissue EngineeringBiological Products

Identifiers

PMID23000743
PMCPMC3548991

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.