ArticleJournal of veterinary science2012
Hsp70 and HSF-1 expression is altered in the tissues of pigs transported for various periods of times.
Article in Journal of veterinary science, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 20 citations in OpenAlex.
- The impact of stress in domestic animals: roles of heat shock proteins and acute-phase proteins.Veterinary research communications · 2025Review
- The Protective Role of Heat Shock Proteins against Stresses in Animal Breeding.International journal of molecular sciences · 2024Review
- Evaluation of a Dietary Grape Extract on Oxidative Status, Intestinal Morphology, Plasma Acute-Phase Proteins and Inflammation Parameters of Weaning Piglets at Various Points of Time.Antioxidants (Basel, Switzerland) · 2022Article
- Physiological and immune responses to long road transportation in Andaman local pigs.Tropical animal health and production · 2021Article
- Effects of zinc oxide nanoparticles on regulatory appetite and heat stress protein genes in broiler chickens subjected to heat stress.Journal of animal science · 2020Article
- The Effects of a Glucocorticoid Receptor Agonist (GRA) on the Immune Function, Nutrient Digestibility, and Wean-to-Finish Growth Performance of Early-Weaned Pigs.Animals : an open access journal from MDPI · 2020Article
- An ethylene response factor (MxERF4) functions as a repressor of Fe acquisition in Malus xiaojinensis.Scientific reports · 2018Article
- Modulatory Effect of Monochromatic Blue Light on Heat Stress Response in Commercial Broilers.Oxidative medicine and cellular longevity · 2017Article
- The ethylene response factor AtERF4 negatively regulates the iron deficiency response in Arabidopsis thaliana.PloS one · 2017Article
- Comparative analysis of αB-crystallin expression in heat-stressed myocardial cells in vivo and in vitro.PloS one · 2014Article
- Localization and expression of Hsp27 and αB-crystallin in rat primary myocardial cells during heat stress in vitro.PloS one · 2013Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to assess changes of Hsp70 and HSF-1 protein and mRNA expression in stress-sensitive organs of pigs during transportation for various periods of time. Twenty pigs were randomly divided into four groups (0 h, 1 h, 2 h, and 4 h of transportation). A significant increased activity of AST and CK was observed after 1 h and 2 h of transportation. Histopathological changes in the heart, liver, and stomach indicated that these organs sustained different degrees of injury. Hsp70 protein expression in the heart and liver of transported pigs did not change significantly while it increased significantly (p < 0.05) in the stomach. Hsp70 mRNA levels decreased significantly (p < 0.05) in the heart after 4 h of transportation. However, mRNA expression increased significantly in the liver after 1 (p < 0.05) and 4 h (p < 0.01) of transportation, and increased significantly in the stomach of the transported pigs after 1, 4 (p < 0.01), and 2 h (p < 0.05). HSF-1 levels were reduced at 1 and 4 h (p < 0.05) only in the hearts of transported pigs. These results indicate that Hsp70 mediates distinct stress-related functions in different tissues during transportation.
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Registered trials
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