Evidence map›Paper›PMID 22999817›Full record

Trial reportDrug and alcohol dependence2013

A randomized trial of intensive outpatient (IOP) vs. standard outpatient (OP) buprenorphine treatment for African Americans.

Shannon Gwin Mitchell, Jan Gryczynski, Robert P Schwartz, Kevin E O'Grady, Yngvild K Olsen, Jerome H Jaffe

Erratum issuedAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Drug and alcohol dependence, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 29 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 6 pooled it
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 6 syntheses or guidelines pooled it, 48 citations in OpenAlex.

  1. Pooled it
  2. Interventions for female drug-using offenders.The Cochrane database of systematic reviews · 2019
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  12. Quality of life measures in treatment for active substance misuse: a scoping review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Shannon Gwin MitchellFriends Research Institute, 1020 Park Avenue, Suite 103, Baltimore, MD 21201, USA. smitchell@friendsresearch.org
Jan Gryczynski
Robert P Schwartz
Kevin E O'Grady
Yngvild K Olsen
Jerome H Jaffe
Friends Research Institute · USInstitutes for Behavior Resources · USUniversity of Maryland, Baltimore · USUniversity of Maryland, College Park · US

Funding

Intensive Outpatient v. Outpatient Treatment with Buprenorphine among African AmeRC1DA028407 · NIDA · FRIENDS RESEARCH INSTITUTE, INC. · PI MITCHELL, SHANNON GWIN · 2009 to 2010
$990k
NIDA NIH HHS RC1 DA028407
6 · The paper itself

Abstract

backgroundBuprenorphine is increasingly being used in community-based treatment programs, but little is known about the optimal level of psychosocial counseling in these settings. The aim of this study was to compare the effectiveness of OP and IOP level counseling when provided as part of buprenorphine treatment for opioid-dependent African Americans.

methodsParticipants were African American men and women starting buprenorphine treatment at one of two community-based clinics (N=300). Participants were randomly assigned to OP or IOP. Measures at baseline, 3- and 6-month included the primary outcome of DSM-IV opioid and cocaine dependence criteria, as well as additional outcomes of illicit opioid and cocaine use (urine test and self-report), criminal activity, retention in treatment, Quality of Life, Addiction Severity Index composite scores, and HIV risk behaviors.

resultsParticipants assigned to OP received, on average, 3.67 (SD=1.30)h of counseling per active week in treatment. IOP participants received an average of 5.23 (SD=1.68)h of counseling per active week (less than the anticipated 9h per week of counseling). Both groups showed substantial improvement over a 6-month period on nearly all measures considered. There were no significant differences between groups in meeting diagnostic criteria for opioid (p=.67) or cocaine dependence (p=.63). There were no significant between group differences on any of the other outcomes. A secondary analysis restricting the sample to participants meeting DSM-IV criteria for baseline cocaine dependence also revealed no significant between-group differences (all ps>.05).

conclusionsBuprenorphine patients receiving OP and IOP levels of care both show short-term improvements.

Indexed as

Ambulatory CareBaltimoreBlack or African AmericanBuprenorphineCocaine-Related DisordersCounselingFemaleHumansMaleOpiate Substitution TreatmentOpioid-Related DisordersBuprenorphine

Identifiers

PMID22999817
PMCPMC3561484
OpenAlexW2005728294

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.