ReviewFertility and sterility2012
Aromatase inhibitors for the treatment of endometriosis.
Review in Fertility and sterility, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- A Systematic Review of Systematic Reviews on the Use of Aromatase Inhibitors for the Treatment of Endometriosis: The Evidence to Date.Drug design, development and therapy · 2023Pooled it
- Is intracrinology of endometriosis relevant in clinical practice? A systematic review on estrogen metabolism.Frontiers in endocrinology · 2022Pooled it
- The Effect of Letrozole Combined with Dydrogesterone for Endometriosis in China: A Meta-Analysis.BioMed research international · 2021Pooled it
- Aromatase inhibitors for uterine fibroids.The Cochrane database of systematic reviews · 2013Pooled it
- Anastrozole and levonorgrestrel-releasing intrauterine device in the treatment of endometriosis: a randomized clinical trial.BMC women's health · 2021Trial
- Hormonal Dysregulation and Neuroinflammation in Endometriosis: Convergent Druggable Pathways.Current issues in molecular biology · 2026Review
- Cancer-like Hallmarks of Endometriosis: The Role of Estrogen Signaling and Stem Cell Plasticity.International journal of molecular sciences · 2026Review
- Insights on Medical Therapy for Uterine Fibroids: A Review.Advances in therapy · 2026Review
- Endometriosis-associated bone loss: re-evaluating the potential role of systemic inflammation and hypoestrogenic therapies.Frontiers in global women's health · 2026Review
- The "double-edged sword" effect of non-steroidal anti-inflammatory drugs (NSAIDs) in the treatment of endometriosis (EMS).Reproductive biology and endocrinology : RB&E · 2025Article
- Understanding Endometriosis: A Broad Review of Its Causes, Management, and Impact.International journal of molecular sciences · 2025Review
- Endometriosis: Challenges in Clinical Molecular Diagnostics and Treatment.International journal of molecular sciences · 2025Review
- The effect of endometriosis on oocyte quality: mechanisms, diagnosis and treatment.Archives of gynecology and obstetrics · 2025Review
- Central Serous Chorioretinopathy in Endometriosis Treatment with Progestogen: A Metabolic Understanding.Life (Basel, Switzerland) · 2025Article
- Management of menopause in women with a history of endometriosis.Journal of the Turkish German Gynecological Association · 2024Article
- Diagnostic and therapeutic approaches for endometriosis: a patent landscape.Archives of gynecology and obstetrics · 2024Review
- An opinion on H1-antihistamines as a potential avenue for endometriosis management.AJOG global reports · 2023Article
- Co-treatment of gonadotropin and letrozole in infertile women with endometriosis: A double-blind randomized clinical trial.International journal of reproductive biomedicine · 2022Article
- Treatment of endometriosis: a review with comparison of 8 guidelines.BMC women's health · 2021Review
- Adenomyosis pathogenesis: insights from next-generation sequencing.Human reproduction update · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
objectiveTo review the use of aromatase inhibitors (AIs) for the treatment of endometriosis.
designLiterature review. CONCLUSION(S): Most studies show that in reproductive-age women, the combination of AI with conventional therapy alleviates endometriosis-related pain. In postmenopausal women, using an AI alone has been shown to be an effective treatment, although more studies are needed in this subgroup. Side effects of using AIs appear to be tolerable in most women, although special consideration should be given to monitoring bone mineral density. More studies need to be done examining pregnancy rates and outcomes after AI treatment for endometriosis. In addition, larger randomized clinical trials using AIs need to be done. In summary, AIs may be effective in treating endometriosis-related chronic pelvic pain in both reproductive-age and postmenopausal women.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.