ArticleBiomedical engineering online2012
Beat-to-beat estimation of the continuous left and right cardiac elastance from metrics commonly available in clinical settings.
Article in Biomedical engineering online, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- First-phase ejection fraction and ventricular-arterial coupling across the lifespan: An in silico analysis.Physiological reports · 2026Article
- Assessment of a non-invasive approach for pressure volume loop prediction in mice.Scientific reports · 2025Article
- An algorithm to detect dicrotic notch in arterial blood pressure and photoplethysmography waveforms using the iterative envelope mean method.Computer methods and programs in biomedicine · 2024Article
- Non-invasive pressure-volume loops using the elastance model and CMR: a porcine validation at transient pre-loads.European heart journal. Imaging methods and practice · 2024Article
- A variable heart rate multi-compartmental coupled model of the cardiovascular and respiratory systems.Journal of the Royal Society, Interface · 2023Article
- Non-invasive left ventricular pressure-volume loops from cardiovascular magnetic resonance imaging and brachial blood pressure: validation using pressure catheter measurements.European heart journal. Imaging methods and practice · 2023Article
- Accurate end systole detection in dicrotic notch-less arterial pressure waveforms.Journal of clinical monitoring and computing · 2021Article
- Minimally invasive, patient specific, beat-by-beat estimation of left ventricular time varying elastance.Biomedical engineering online · 2017Article
- Minimally invasive estimation of ventricular dead space volume through use of Frank-Starling curves.PloS one · 2017Article
- A Zero-Dimensional Model and Protocol for Simulating Patient-Specific Pulmonary Hemodynamics From Limited Clinical Data.Journal of biomechanical engineering · 2016Article
- Simulation of left atrial function using a multi-scale model of the cardiovascular system.PloS one · 2014Article
- Evaluation of a model-based hemodynamic monitoring method in a porcine study of septic shock.Computational and mathematical methods in medicine · 2013Article
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Authors and funding
9 authors.
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Abstract
introductionFunctional time-varying cardiac elastances (FTVE) contain a rich amount of information about the specific cardiac state of a patient. However, a FTVE waveform is very invasive to directly measure, and is thus currently not used in clinical practice. This paper presents a method for the estimation of a patient specific FTVE, using only metrics that are currently available in a clinical setting.
methodCorrelations are defined between invasively measured FTVE waveforms and the aortic and pulmonary artery pressures from 2 cohorts of porcine subjects, 1 induced with pulmonary embolism, the other with septic shock. These correlations are then used to estimate the FTVE waveform based on the individual aortic and pulmonary artery pressure waveforms, using the "other" dysfunction's correlations as a cross validation.
resultsThe cross validation resulted in 1.26% and 2.51% median errors for the left and right FTVE respectively on pulmonary embolism, while the septic shock cohort had 2.54% and 2.90% median errors.
conclusionsThe presented method accurately and reliably estimated a patient specific FTVE, with no added risk to the patient. The cross validation shows that the method is not dependent on dysfunction and thus has the potential for generalisation beyond pulmonary embolism and septic shock.
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