Evidence map›Paper›PMID 22998777›Full record

ReviewTransfusion2013

Scratching the surface of allergic transfusion reactions.

William J Savage, Aaron A R Tobian, Jessica H Savage, Robert A Wood, John T Schroeder, Paul M Ness

Abstract readReview
In one paragraph

Review in Transfusion, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
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  8. Article
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  10. Article
  11. The use of premedications for platelet transfusions in pediatric patients.Hematology. American Society of Hematology. Education Program · 2020
    Review
  12. Surveillance of Transfusion Related Adverse Reactions in a Tertiary Care Centre in Bangalore: A 4-Year Hemovigilance Initiative.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2020
    Article
  13. Article
  14. Peanut and fish allergy due to platelet transfusion in a child.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2015
    Article
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

William J SavageDivision of Transfusion Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. wjsavage@partners.org
Aaron A R Tobian
Jessica H Savage
Robert A Wood
John T Schroeder
Paul M Ness

Funding

Mechanisms of Allergic Transfusion ReactionsR21HL107828 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI SAVAGE, WILLIAM · 2012 to 2013
$466k
NHLBI NIH HHS R21 HL107828NHLBI NIH HHS R21HL107828
6 · The paper itself

Abstract

Allergic transfusion reactions (ATRs) are a spectrum of hypersensitivity reactions that are the most common adverse reaction to platelets and plasma, occurring in up to 2% of transfusions. Despite the ubiquity of these reactions, little is known about their mechanism. In a small subset of severe reactions, specific antibody has been implicated as causal, although this mechanism does not explain all ATRs. Evidence suggests that donor, product, and recipient factors are involved, and it is possible that many ATRs are multifactorial. Further understanding of the mechanisms of ATRs is necessary so that rationally designed and cost-effective prevention measures can be developed.

Indexed as

Blood Group IncompatibilityBlood PlateletsBlood ProteinsHumansHypersensitivityPlatelet TransfusionTransfusion ReactionBlood Proteins

Identifiers

PMID22998777
PMCPMC3711222

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.