ArticleGenetics2012
Trade-off between selection for dosage compensation and masculinization on the avian Z chromosome.
Article in Genetics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
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Who cites it
47 citing papers in PubMed, 73 citations in OpenAlex.
- Selective Regimes and Evolutionary Dynamics of Z and W Gametologs Across an Expanded Avian Neo-Sex Chromosome.Genome biology and evolution · 2026Article
- Sex-biased expression of sex-linked transcripts in spiny frogs with homomorphic sex chromosomes.BMC genomics · 2025Article
- Faster adaptation but slower divergence of X chromosomes under paternal genome elimination.Nature communications · 2025Article
- Role-reversed polyandry is associated with faster fast-Z in shorebirds.Proceedings. Biological sciences · 2024Article
- A sex-linked supergene with large effects on sperm traits has little impact on reproductive traits in female zebra finches.Proceedings. Biological sciences · 2024Article
- Evolution, Inheritance, and Strata Formation of the W Chromosome in Duck (Anas platyrhynchos).Genome biology and evolution · 2023Article
- Are plant and animal sex chromosomes really all that different?Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Review
- Support for faster and more adaptive Z chromosome evolution in two divergent lepidopteran lineagesEvolution; international journal of organic evolution · 2022Article
- Genetic Regulation of Avian Testis Development.Genes · 2021Review
- Highly Conservative Pattern of Sex Chromosome Synapsis and Recombination in Neognathae Birds.Genes · 2021Article
- Transcriptomic and Epigenetic Preservation of Genetic Sex Identity in Estrogen-feminized Male Chicken Embryonic Gonads.Endocrinology · 2021Article
- Genome assembly of the basket willow, Salix viminalis, reveals earliest stages of sex chromosome expansion.BMC biology · 2020Article
- Sex Chromosome Evolution: So Many Exceptions to the Rules.Genome biology and evolution · 2020Review
- Guppy Y Chromosome Integrity Maintained by Incomplete Recombination Suppression.Genome biology and evolution · 2020Article
- Differential Gene Expression between Fungal Mating Types Is Associated with Sequence Degeneration.Genome biology and evolution · 2020Article
- How to identify sex chromosomes and their turnover.Molecular ecology · 2019Review
- Sexual conflict through mother's curse and father's curse.Theoretical population biology · 2019Article
- Phenotypic sexual dimorphism is associated with genomic signatures of resolved sexual conflict.Molecular ecology · 2019Article
- Sex-Biased Gene Expression and Dosage Compensation on the Artemia franciscana Z-Chromosome.Genome biology and evolution · 2019Article
- A Genetic Map of Ostrich Z Chromosome and the Role of Inversions in Avian Sex Chromosome Evolution.Genome biology and evolution · 2018Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Following the suppression of recombination, gene expression levels decline on the sex-limited chromosome, and this can lead to selection for dosage compensation in the heterogametic sex to rebalance average expression from the X or Z chromosome with average autosomal expression. At the same time, due to their unequal pattern of inheritance in males and females, the sex chromosomes are subject to unbalanced sex-specific selection, which contributes to a nonrandom distribution of sex-biased genes compared to the remainder of the genome. These two forces act against each other, and the relative importance of each is currently unclear. The Gallus gallus Z chromosome provides a useful opportunity to study the importance and trade-offs between sex-specific selection and dosage compensation in shaping the evolution of the genome as it shows incomplete dosage compensation and is also present twice as often in males than females, and therefore predicted to be enriched for male-biased genes. Here, we refine our understanding of the evolution of the avian Z chromosome, and show that multiple strata formed across the chromosome over ∼130 million years. We then use this evolutionary history to examine the relative strength of selection for sex chromosome dosage compensation vs. the cumulative effects of masculinizing selection on gene expression. We find that male-biased expression increases over time, indicating that selection for dosage compensation is relatively less important than masculinizing selection in shaping Z chromosome gene expression.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.