ArticleJournal of microbiology (Seoul, Korea)2012
Regulatory characteristics of the Vibrio vulnificus rtxHCA operon encoding a MARTX toxin.
Article in Journal of microbiology (Seoul, Korea), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- Rifampicin-resistant RpoB S522L Vibrio vulnificus exhibits disturbed stress response and hypervirulence traits.MicrobiologyOpen · 2023Article
- Vibrio vulnificus PlpA facilitates necrotic host cell death induced by the pore forming MARTX toxin.Journal of microbiology (Seoul, Korea) · 2022Article
- Spatiotemporal Regulation ofToxins · 2020Review
- A MARTX ToxinmBio · 2020Article
- VvpM, an extracellular metalloprotease of Vibrio vulnificus, induces apoptotic death of human cells.Journal of microbiology (Seoul, Korea) · 2014Article
- Low cell density regulator AphA upregulates the expression of Vibrio vulnificus iscR gene encoding the Fe-S cluster regulator IscR.Journal of microbiology (Seoul, Korea) · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vibrio vulnificus MARTX encoded by rtxA, an open reading frame of the rtxHCA operon, is essential for virulence in vitro and in mice. In this study, a primer extension analysis revealed that transcription of the rtxHCA operon begins at a single site, and is under the direction of a single promoter, P( rtxHCA ). P( rtxHCA ) activity appeared at the beginning of growth and reached a maximum in mid-exponential phase. P( rtxHCA ) activity was induced by exposure to INT-407 cells, and the membrane fraction of INT-407 cells was the most effective for the induction.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.