Evidence map›Paper›PMID 22996729›Full record

ArticleCurrent microbiology2012

Response of P. aeruginosa E(1) gene expression to cadmium stress.

Xiaoxi Zeng, Jianxin Tang, Xueduan Liu, Pei Jiang

Abstract read
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In one paragraph

Article in Current microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Variability in cadmium tolerance of closely relatedApplied and environmental microbiology · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xiaoxi ZengHunan Key Lab of Green Packaging and Biological Nanotechnology, Hunan University of Technology, Zhuzhou 412007, People's Republic of China. zengxiaoxi2003@163.com
Jianxin Tang
Xueduan Liu
Pei Jiang

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heavy metal resistance microorganism plays an important role on polluted soil bioremediation. To obtain further knowledge of the resistant mechanism employed by cadmium-resistant bacteria, some gene expression profiles at transcription level were investigated in P. aeruginosa E(1) subjected to cadmium stress using real-time PCR. Exposure to cadmium for 1 h, the expression of czcA, czcB, and czcC all reached the peak of up-regulation 8.82-, 4.83-, and 7.43-fold, respectively. The response of czcD was earlier and stronger than czcABC. CysM contributed to cysteine synthesis kept up-regulation within the beginning 2 h. The expression of mgtAE genes related to Mg(2+) influx was up-regulated all the while, znuB responsible for Zn(2+) transportation kept up-regulation from 30 min to 4 h. The result support the two cadmium-resistance mechanisms including effluxing and inactive the heavy metal ions. The mechanism was brought that increase of Mg(2+) and Zn(2+) in cytoplasm would prevent Cd(2+)-binding enzymes to decrease the harm to cell.

Indexed as

Bacterial ProteinsCadmiumGene Expression ProfilingGene Expression Regulation, BacterialMetals, HeavyPseudomonas aeruginosaReal-Time Polymerase Chain ReactionUp-RegulationBacterial ProteinsCadmiumMetals, Heavy

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.