ArticleBiophysical journal2012
Thermal transitions of fibrillar collagen unveiled by second-harmonic generation microscopy of corneal stroma.
Article in Biophysical journal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- An Optimized Staining Method for Visualization of Thermally Denatured Dermal Collagen.Lasers in surgery and medicine · 2026Article
- Functional and analytical recapitulation of osteoclast biology on demineralized bone paper.Nature communications · 2023Article
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- Multiview deconvolution approximation multiphoton microscopy of tissues and zebrafish larvae.Scientific reports · 2021Article
- Assessment of the corneal collagen organization after chemical burn using second harmonic generation microscopy.Biomedical optics express · 2021Article
- Recent Advances in Fluorescence Imaging of Pulmonary Fibrosis in Animal Models.Frontiers in molecular biosciences · 2021Review
- In Vitro Feasibility Analysis of a New Sutureless Wound-Closure System Based on a Temperature-Regulated Laser and a Transparent Collagen Membrane for Laser Tissue Soldering (LTS).International journal of molecular sciences · 2020Article
- Light-Activated Tissue-Integrating Sutures as Surgical Nanodevices.Advanced healthcare materials · 2019Article
- Spatiotemporal modeling of laser tissue soldering using photothermal nanocomposites.Lasers in surgery and medicine · 2018Article
- Article
- Influences of thermal environment on fish growth.Ecology and evolution · 2017Article
- SHG-specificity of cellular Rootletin filaments enables naïve imaging with universal conservation.Scientific reports · 2017Article
- Non-covalent photo-patterning of gelatin matrices using caged collagen mimetic peptides.Macromolecular bioscience · 2015Article
- Nanomechanical mapping of hydrated rat tail tendon collagen I fibrils.Biophysical journal · 2014Article
- Clinical nonlinear laser imaging of human skin: a review.BioMed research international · 2014Review
- Microstructural characterization of vocal folds toward a strain-energy model of collagen remodeling.Acta biomaterialia · 2013Article
Corrections and comments
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Authors and funding
8 authors.
Funding
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Abstract
The thermal transitions of fibrillar collagen are investigated with second-harmonic generation polarization anisotropy microscopy. Second-harmonic generation images and polarization anisotropy profiles of corneal stroma heated in the 35-80°C range are analyzed by means of a theoretical model that is suitable to probe principal intramolecular and interfibrillar parameters of immediate physiological interest. Our results depict the tissue modification with temperature as the interplay of three destructuration stages at different hierarchical levels of collagen assembly including its tertiary structure and interfibrillar alignment, thus supporting and extending previous findings. This method holds the promise of a quantitative inspection of fundamental biophysical and biochemical processes and may find future applications in real-time and postsurgical functional imaging of collagen-rich tissues subjected to thermal treatments.
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