Evidence map›Paper›PMID 22995343›Full record

ReviewCurrent opinion in cell biology2012

Outfits for different occasions: tissue-specific roles of Nuclear Envelope proteins.

J Sebastian Gomez-Cavazos, Martin W Hetzer

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in cell biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 43 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Nuclear organization and regulation of the differentiated state.Cellular and molecular life sciences : CMLS · 2021
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Article
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  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

J Sebastian Gomez-CavazosSalk Institute for Biological Studies, Molecular and Cell Biology Laboratory, 10010N. Torrey Pines Road, La Jolla, 92037 CA, United States.
Martin W Hetzer
Salk Institute for Biological Studies · US

Funding

Viral Vector Core (VVC)P30CA014195 · NCI · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI Ye Zheng · 1985 to 2026
$82.8M
The role of the nucleoporin Nup98 in gene regulationR01GM098749 · NIGMS · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI HETZER, MARTIN W · 2012 to 2015
$1.4M
NCI NIH HHS P30 CA014195NIGMS NIH HHS GM098749NIGMS NIH HHS R01 GM098749
6 · The paper itself

Abstract

The Nuclear Envelope (NE) contains over 100 different proteins that associate with nuclear components such as chromatin, the lamina and the transcription machinery. Mutations in genes encoding NE proteins have been shown to result in tissue-specific defects and disease, suggesting cell-type specific differences in NE composition and function. Consistent with these observations, recent studies have revealed unexpected functions for numerous NE associated proteins during cell differentiation and development. Here we review the latest insights into the roles played by the NE in cell differentiation, development, disease and aging, focusing primarily on inner nuclear membrane (INM) proteins and nuclear pore components.

Indexed as

DiseaseAgingAnimalsCell CompartmentationCell DifferentiationChromatinHumansMembrane ProteinsNuclear EnvelopeNuclear PoreOrgan SpecificitySignal TransductionChromatinMembrane Proteins

Identifiers

PMID22995343
PMCPMC3587307
OpenAlexW1995560468

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.