Evidence map›Paper›PMID 22995171›Full record

ArticleCell & bioscience2012

Nuclear hormone receptors in podocytes.

Simran Khurana, Leslie A Bruggeman, Hung-Ying Kao

Open access · goldAbstract read
In one paragraph

Article in Cell & bioscience, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Review
  3. Vitamin D and Glomerulonephritis.Medicina (Kaunas, Lithuania) · 2021
    Review
  4. Maintenance of Kidney Metabolic Homeostasis by PPAR Gamma.International journal of molecular sciences · 2018
    Review
  5. Prospects for Precision Medicine in Glomerulonephritis Treatment.Canadian journal of kidney health and disease · 2018
    Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Simran KhuranaDepartment of Biochemistry, School of Medicine, Case Western Reserve University (CWRU) and the Comprehensive Cancer Center of CWRU, 10900 Euclid Avenue, Cleveland, Ohio 44106, USA. hxk43@cwru.edu.
Leslie A Bruggeman
Hung-Ying Kao
Case Western Reserve University · USMetroHealth Medical Center · US

Funding

Alpha actinin 4: its functions and regulationR01DK078965 · NIDDK · CASE WESTERN RESERVE UNIVERSITY · PI KAO, HUNG-YING · 2009 to 2013
$1.7M
Histone deacetylase 7 and its interacting proteins in endothelial cellsR01HL093269 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI KAO, HUNG-YING · 2010 to 2013
$1.5M
NHLBI NIH HHS R01 HL093269NIDDK NIH HHS R01 DK078965
6 · The paper itself

Abstract

Nuclear receptors are a family of ligand-activated, DNA sequence-specific transcription factors that regulate various aspects of animal development, cell proliferation, differentiation, and homeostasis. The physiological roles of nuclear receptors and their ligands have been intensively studied in cancer and metabolic syndrome. However, their role in kidney diseases is still evolving, despite their ligands being used clinically to treat renal diseases for decades. This review will discuss the progress of our understanding of the role of nuclear receptors and their ligands in kidney physiology with emphasis on their roles in treating glomerular disorders and podocyte injury repair responses.

Identifiers

PMID22995171
PMCPMC3543367
OpenAlexW2135435308

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.