ArticleRadiology2012
Short-term mortality in acute pulmonary embolism: clot burden and signs of right heart dysfunction at CT pulmonary angiography.
Article in Radiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers, 2 of them syntheses that pooled it.
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Who cites it
85 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Sex as a prognostic factor for mortality in adults with acute symptomatic pulmonary embolism.The Cochrane database of systematic reviews · 2025Pooled it
- Catheter-directed therapies for the treatment of high risk (massive) and intermediate risk (submassive) acute pulmonary embolism.The Cochrane database of systematic reviews · 2022Pooled it
- A Promptable 3D-CT Foundation Model-Based Approach for Pulmonary Embolism.Cardiovascular and interventional radiology · 2026Article
- Development and validation of a pulmonary embolism quantification method using single photon emission computed tomography ventilation and perfusion scintigraphy.EJNMMI research · 2026Article
- Influence of patients' sex on radiomics-based predictions of lung artery thrombus.International journal of computer assisted radiology and surgery · 2026Article
- Evaluation of the relationship between thrombus burden, inflammation indices, and prognosis in central and peripheral pulmonary embolism.Thrombosis journal · 2026Article
- Quantitative assessment of risk stratification of acute pulmonary embolism based on three-dimensional computed tomography bronchography and angiography.Journal of thoracic disease · 2026Article
- Deep learning-based segmentation of acute pulmonary embolism in cardiac CT images.International journal of computer assisted radiology and surgery · 2026Article
- Prognostic potential of radiomics evaluation of lung artery thrombus for pulmonary embolism patients.International journal of computer assisted radiology and surgery · 2026Article
- Contrast Reflux Into IVC in Acute Pulmonary Embolism Predicts Clinical Deterioration Risk.Pulmonary circulation · 2026Article
- Developing a novel deep learning-based model for automatic right ventricular parameters assessment on ctpa in pulmonary embolism.Emergency radiology · 2025Article
- Cardiopulmonary Exercise Testing in People With Dyspnea With a Recent Acute Pulmonary Embolism.CHEST pulmonary · 2025Article
- Simplified computed tomography pulmonary angiography score predicts clinical deterioration in patients with acute pulmonary embolism.International journal of cardiology. Heart & vasculature · 2025Article
- Predicting Deterioration in Patients With Normotensive Acute Pulmonary Embolism Using Clinical-Imaging Features: A Multicenter Prospective Cohort Study.Journal of the American Heart Association · 2025Observational
- Comparison of 30-Day Readmission Between Early and Late Catheter Directed Thrombolysis for Acute Pulmonary Embolism in the United States.Journal of cardiovascular development and disease · 2025Article
- Characteristics, management and outcomes of central versus peripheral pulmonary embolism: a retrospective cohort study.Thrombosis journal · 2025Article
- Quantitative assessment and risk stratification of random acute pulmonary embolism cases using a deep learning model based on computed tomography pulmonary angiography images.Quantitative imaging in medicine and surgery · 2025Article
- The Role of the Pulmonary Artery Obstruction Index Ratio in Predicting the Clinical Course of Pulmonary Embolism.Journal of clinical medicine · 2025Article
- COVID-19: A Disease Driven by Protease/Antiprotease Imbalance? A Specific Review Five Years into the Pandemic.Infection and drug resistance · 2025Review
- Current Role of CT Pulmonary Angiography in Pulmonary Embolism: A State-of-the-Art Review.Journal of imaging · 2024Review
25 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
purposeTo assess the correlation between volumetric measurements of clot, semiquantitative clot burden indexes, and signs of right heart dysfunction at computed tomographic (CT) pulmonary angiography in patients with acute pulmonary embolism (PE) and to determine whether clot burden and signs of right heart dysfunction are associated with short-term mortality. MATERIALS AND
methodsThis retrospective study was institutional review board approved and HIPAA compliant. CT pulmonary angiographic studies (January 2007 through December 2007) with findings positive for PE were retrieved. Two readers evaluated signs of right heart dysfunction at CT pulmonary angiography, measured clot volume using a dedicated software program, and assessed clot burden using semiquantitative scores (Qanadli and Mastora). Spearman rank coefficient was used to investigate correlation between clot burden measures and signs of right heart dysfunction. Uni- and multivariate analyses were used to test association between CT pulmonary angiographic findings and short-term mortality.
resultsA total of 635 CT pulmonary angiographic studies from 635 patients (304 men, 331 women; mean age, 59 years) were included; 39 (6%) patients died within 30 days. Clot volume was strongly correlated with Qanadli score (ρ=0.841, P<.01) and Mastora score (ρ=0.863, P<.01) and moderately correlated (ρ=0.378, P<.01) with the ratio of right ventricle diameter to left ventricle diameter (RV/LV ratio). Among the pulmonary angiographic signs, only increase in RV/LV ratio (cut-off value, 1.0) was independently associated with short-term mortality in multivariate analysis.
conclusionClot volume strongly correlated with semiquantitative CT scores of clot burden, and greater clot volume was associated with higher incidence of right heart dilatation. Increase in RV/LV ratio was associated with short-term mortality; however, measures of clot burden were not.
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