Evidence map›Paper›PMID 22993184›Full record

ArticleJournal of clinical microbiology2012

Genotypic resistance testing creates new treatment challenges: two cases of oxacillin-susceptible methicillin-resistant Staphylococcus aureus.

Katie A Sharff, Stefan Monecke, Sarah Slaughter, Graeme Forrest, Chris Pfeiffer, Ralf Ehricht, Margret Oethinger

Abstract readCase Reports
In one paragraph

Article in Journal of clinical microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Phenotypic and genomic characteristics of oxacillin-susceptible mecA-positive Staphylococcus aureus, rapid selection of high-level resistance to beta-lactams.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Katie A SharffDivision of Infectious Diseases, Oregon Health and Science University, Portland, Oregon, USA. sharffk@ohsu.edu
Stefan Monecke
Sarah Slaughter
Graeme Forrest
Chris Pfeiffer
Ralf Ehricht
Margret Oethinger

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxacillin-susceptible, mecA-positive Staphylococcus aureus isolates create a treatment challenge for the clinician. In this article, we describe two cases of bacteremia from isolates that carried the mecA gene but were susceptible to oxacillin (oxacillin-susceptible methicillin-resistant S. aureus [OS-MRSA]). DNA microarray analysis was used to characterize these isolates as a mecA-positive, clonal complex 5, pediatric strain and a mecA-positive, clonal complex 8, USA300 strain.

Indexed as

Anti-Bacterial AgentsBacteremiaBacterial ProteinsHumansMaleMethicillin-Resistant Staphylococcus aureusMicroarray AnalysisMicrobial Sensitivity TestsMiddle AgedOxacillinPenicillin-Binding ProteinsStaphylococcal InfectionsAnti-Bacterial AgentsBacterial ProteinsmecA protein, Staphylococcus aureusOxacillinPenicillin-Binding Proteins

Identifiers

PMID22993184
PMCPMC3502964

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.