Evidence map›Paper›PMID 22992357›Full record

Trial reportAmerican journal of preventive medicine2012

Family history assessment: impact on disease risk perceptions.

Catharine Wang, Ananda Sen, Mack T Ruffin, Donald E Nease, Robert Gramling, Louise S Acheson, Suzanne M O'Neill, Wendy S Rubinstein, Family Healthware™ Impact Trial (FHITr) Group

Abstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in American journal of preventive medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Genetic cancer risk assessment in general practice: systematic review of tools available, clinician attitudes, and patient outcomes.The British journal of general practice : the journal of the Royal College of General Practitioners · 2019
    Pooled it
  4. Pooled it
  5. The Effects of Personalizing Colorectal Cancer Risk Communication on Risk Perceptions and Health Behavior Intentions: a Randomized Trial of Average-Risk Adults.Journal of cancer education : the official journal of the American Association for Cancer Education · 2021
    Trial
  6. Trial
  7. User Perceptions and Reactions to an Online Cancer Risk Assessment Tool: a Process Evaluation of Cancer Risk Check.Journal of cancer education : the official journal of the American Association for Cancer Education · 2017
    Trial
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  11. Article
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  15. Review
  16. Development and Validation of Lifestyle-Based Models to Predict Incidence of the Most Common Potentially Preventable Cancers.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2019
    Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Catharine WangDepartment of Community Health Sciences, Boston University School of Public Health, Boston, MA 02118, USA. clwang@bu.edu
Ananda Sen
Mack T Ruffin
Donald E Nease
Robert Gramling
Louise S Acheson
Suzanne M O'Neill
Wendy S Rubinstein
Family Healthware™ Impact Trial (FHITr) Group

Funding

Clinical and Translational Science Collaborative of ClevelandUL1TR000439 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI KONSTAN, MICHAEL W. · 2012 to 2016
$50.0M
Communication of Genetic and Environmental Risks in Colorectal Cancer PreventionK07CA131103 · NCI · FOX CHASE CANCER CENTER · PI WANG, CATHARINE · 2008 to 2012
$674k
THE 'GREAT'SYSTEM TO IDENTIFY FAMILIAL CANCER RISKK07CA086958 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI ACHESON, LOUISE SEYMOUR · 2000 to 2005
$656k
NCATS NIH HHS UL1 TR000439NCI NIH HHS K07 CA086958NCI NIH HHS K07 CA131103
6 · The paper itself

Abstract

backgroundFamily Healthware™, a tool developed by the CDC, is a self-administered web-based family history tool that assesses familial risk for six diseases (coronary heart disease; stroke; diabetes; and colon, breast, and ovarian cancers) and provides personalized prevention messages based on risk. The Family Healthware Impact Trial (FHITr) set out to examine the clinical utility of presenting personalized preventive messages tailored to family history risk for improving health behaviors. PURPOSE: The purpose of this study was to examine the impact of Family Healthware on modifying disease risk perceptions, particularly among those who initially underestimated their risk for certain diseases.

designA total of 3786 patients were enrolled in a cluster-randomized trial to evaluate the clinical utility of Family Healthware. SETTING/

participantsParticipants were recruited from 41 primary care practices among 13 states between 2005 and 2007.

main outcome measuresPerceived risk for each disease was assessed at baseline and 6-month follow-up using a single-item comparative risk question. Analyses were completed in March 2012.

resultsCompared to controls, Family Healthware increased risk perceptions among those who underestimated their risk for heart disease (15% vs 9%, p<0.005); stroke (11% vs 8%, p<0.05); diabetes (18% vs 11%, p<0.05); and colon cancer (17% vs 10%, p=0.05) but not breast or ovarian cancers. The majority of underestimators did not shift in their disease risk perceptions.

conclusionsFamily Healthware was effective at increasing disease risk perceptions, particularly for metabolic conditions, among those who underestimated their risk. Results from this study also demonstrate the relatively resistant nature of risk perceptions.

trial registrationThis study is registered at clinicaltrials.govNCT00164658.

Indexed as

Attitude to HealthFamily HealthHealth BehaviorInternetCenters for Disease Control and Prevention, U.S.Chronic DiseaseCluster AnalysisFemaleFollow-Up StudiesHumansMaleMiddle AgedPrimary Health CareRiskRisk AssessmentRisk Factors

Identifiers

PMID22992357
PMCPMC3448124

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.