ArticleClinical and translational allergy2012
Dysfunctional breathing phenotype in adults with asthma - incidence and risk factors.
Article in Clinical and translational allergy, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07397676 (Effects of Breathing Technique Training and Physical Activity Counseling on Quality of Life, Symptoms, Asthma Control, and Physical Activity in Children and Adolescents With Asthma), which is not on this map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Breathing Technique Training and Physical Activity Counseling on Quality of Life, Symptoms, Asthma Control, and Physical Activity in Children and Adolescents With Asthma: A Randomized Controlled Trial
Who cites it
20 citing papers in PubMed, 57 citations in OpenAlex.
- Validation of the Paediatric Nijmegen Questionnaire in Sweden: A Self-Screening Tool for Dysfunctional Breathing.The clinical respiratory journal · 2026Article
- A comprehensive comparison of primary hyperventilation syndrome versus hyperventilation syndrome secondary to respiratory infections.BMC infectious diseases · 2026Article
- Living with breathing pattern disorder: a scoping review.NPJ primary care respiratory medicine · 2026Article
- Assessing ventilatory efficiency at rest in asthma: A longitudinal comparison with healthy subjects.Physiological reports · 2025Article
- Puzzled by dysfunctional breathing disorder(s)? Consider the Bayesian brain hypothesis!Frontiers in neuroscience · 2023Article
- Associations of symptoms of anxiety and depression with health-status, asthma control, dyspnoea, dysfunction breathing and obesity in people with severe asthma.Respiratory research · 2022Article
- Neck Pain and Disability: Are They Related to Dysfunctional Breathing and Stress?Physiotherapy Canada. Physiotherapie Canada · 2022Article
- The Detrimental Clinical Associations of Anxiety and Depression with Difficult Asthma Outcomes.Journal of personalized medicine · 2022Article
- Changes in quantifiable breathing pattern components predict asthma control: an observational cross-sectional study.Asthma research and practice · 2021Article
- Physical Activity: A Missing Link in Asthma Care.Journal of clinical medicine · 2020Review
- The Optimal Cut-off Score of the Nijmegen Questionnaire for Diagnosing Hyperventilation Syndrome Using a Bayesian Model in the Absence of a Gold Standard.Galen medical journal · 2020Article
- Article
- Dysfunctional breathing: what do we know?Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2019Review
- Dysfunctional Breathing in Children and Adults With Asthma.Frontiers in pediatrics · 2018Review
- Breathing training for dysfunctional breathing in asthma: taking a multidimensional approach.ERJ open research · 2017Review
- Mechanisms, measurement and management of exertional dyspnoea in asthma: Number 5 in the Series "Exertional dyspnoea" Edited by Pierantonio Laveneziana and Piergiuseppe Agostoni.European respiratory review : an official journal of the European Respiratory Society · 2017Review
- Advances in the Evaluation of Respiratory Pathophysiology during Exercise in Chronic Lung Diseases.Frontiers in physiology · 2017Review
- Dysfunctional breathing: a review of the literature and proposal for classification.European respiratory review : an official journal of the European Respiratory Society · 2016Review
- Is there an association between postural balance and pulmonary function in adults with asthma?Clinics (Sao Paulo, Brazil) · 2013Article
- Cramps and tingling: A diagnostic conundrum.Anesthesia, essays and researchesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
unlabelled
backgroundAbnormal breathing patterns may cause characteristic symptoms and impair quality of life. In a cross-sectional survey 29% of adults treated for asthma in primary care had symptoms suggestive of dysfunctional breathing (DB), more likely to be female and younger, with no differences for severity of asthma. No clear risk factors were demonstrated for DB in asthma, nor the impact of asthma medication was evaluated. The objective of this study was to describe the DB phenotype in adults with asthma treated in a specialised asthma centre.
methodsAdult patients aged 17-65 with diagnosed asthma were screened for DB using the Nijmegen questionnaire (positive predictive score >23) and confirmed by progressive exercise testing. The following were evaluated as independent risk factors for DB in the multiple regression analysis: female sex; atopy, obesity, active smoker, moderate/severe rhinitis, psychopathology, GERD, arterial hypertension; severe asthma, asthma duration > 5 years, lack of asthma control, fixed airway obstruction, fast lung function decline, frequent exacerbator and brittle asthma phenotypes; lack of ICS, use of LABA or LTRA.
results91 adults with asthma, mean age 35.04 ±1.19 years, 47(51.65%) females were evaluated. 27 (29.67%) subjects had a positive screening score on Nijmegen questionnaire and 16(17.58%) were confirmed by progressive exercise testing as having DB. Independent risk factors for DB were psychopathology (p = 0.000002), frequent exacerbator asthma phenotype (p = 0.01) and uncontrolled asthma (p < 0.000001).
conclusionDysfunctional breathing is not infrequent in asthma patients and should be evaluated in asthma patients presenting with psychopathology, frequent severe asthma exacerbations or uncontrolled asthma. Asthma medication (ICS, LABA or LTRA) had no significant relation with dysfunctional breathing.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.