ArticleJournal of the American Chemical Society2012
Site-selective chemistry and the attachment of peptides to the surface of a microelectrode array.
Article in Journal of the American Chemical Society, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed.
- Microelectrode Arrays, Electrocatalysis, and the Need for Proper Characterization.ChemElectroChem · 2023Article
- Lessons from an Array: Using an Electrode Surface to Control the Selectivity of a Solution-Phase Chemical Reaction.Angewandte Chemie (International ed. in English) · 2022Article
- Microelectrode arrays, electrosynthesis, and the optimization of signaling on an inert, stable surface.Beilstein journal of organic chemistry · 2022Article
- Capitalizing on Mediated Electrolyses for the Construction of Complex, Addressable Molecular Surfaces.The Journal of organic chemistry · 2021Article
- From Molecules to Molecular Surfaces. Exploiting the Interplay Between Organic Synthesis and Electrochemistry.Accounts of chemical research · 2020Review
- Electroorganic Synthesis and the Construction of Addressable Molecular Surfaces.ChemElectroChem · 2019Article
- Microelectrode Arrays and the Use of PEG-Functionalized Diblock Copolymer Coatings.Biosensors · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Peptides have been site-selectively placed on microelectrode arrays with the use of both thiol-based conjugate additions and Cu(I)-coupling reactions between thiols and aryl halides. The conjugate addition reactions used both acrylate and maleimide Michael acceptors. Of the two methods, the Cu(I)-coupling reactions proved far superior because of their irreversibility. Surfaces constructed with the conjugate addition chemistry were not stable at neutral pHs, especially the surface using the maleimide acceptor. Once a peptide was placed onto the array, it could be monitored in "real-time" for its interactions with a biological receptor.
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Registered trials
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