Evidence map›Paper›PMID 22991652›Full record

ArticleJournal of nucleic acids2012

Recent advances in chemical modification of Peptide nucleic acids.

Eriks Rozners

Open access · goldAbstract read
In one paragraph

Article in Journal of nucleic acids, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 53 citations in OpenAlex.

  1. Current issues in molecular biology · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Targeting RNA editing of antizyme inhibitor 1: A potential oligonucleotide-based antisense therapy for cancer.Molecular therapy : the journal of the American Society of Gene Therapy · 2021
    Article
  6. Review
  7. Article
  8. miR-7 Knockdown by Peptide Nucleic Acids in the AscidianInternational journal of molecular sciences · 2019
    Article
  9. Article
  10. A Lucifer-Based Environment-Sensitive Fluorescent PNA Probe for Imaging Poly(A) RNAs.Chembiochem : a European journal of chemical biology · 2018
    Article
  11. Artificial Activation ofFrontiers in microbiology · 2018
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Synthesis of PNA oligoether conjugates.Molecules (Basel, Switzerland) · 2014
    Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Eriks RoznersDepartment of Chemistry, Binghamton University, State University of New York, 4400 Vestal Parkway East, Binghamton, NY 13902, USA.
Binghamton University · US

Funding

Amide-Modified RNA: Synthesis, Structure and Potential for RNA InterferenceR01GM071461 · NIGMS · STATE UNIVERSITY OF NY,BINGHAMTON · PI ROZNERS, ERIKS · 2007 to 2017
$3.2M
NIGMS NIH HHS R01 GM071461
6 · The paper itself

Abstract

Peptide nucleic acid (PNA) has become an extremely powerful tool in chemistry and biology. Although PNA recognizes single-stranded nucleic acids with exceptionally high affinity and sequence selectivity, there is considerable ongoing effort to further improve properties of PNA for both fundamental science and practical applications. The present paper discusses selected recent studies that improve on cellular uptake and binding of PNA to double-stranded DNA and RNA. The focus is on chemical modifications of PNA's backbone and heterocyclic nucleobases. The paper selects representative recent studies and does not attempt to provide comprehensive coverage of the broad and vibrant field of PNA modification.

Identifiers

PMID22991652
PMCPMC3443988
OpenAlexW2154495644

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.