Evidence map›Paper›PMID 22990871›Full record

ArticleIntensive care medicine2013

Visual anatomical lung CT scan assessment of lung recruitability.

Davide Chiumello, Antonella Marino, Matteo Brioni, Federica Menga, Irene Cigada, Marco Lazzerini, Maria C Andrisani, Pietro Biondetti, Bruno Cesana, Luciano Gattinoni

Registry-linked trialOpen access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Intensive care medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07328997 (Exploration of Diagnosis and Treatment Strategies and Prognostic Prediction Models for Acute Respiratory Distress Syndrome Based on Radiographic Evaluations Assessed by Artificial Intelligence), which is not on this map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07328997 completednot on this mapstarted 2024, after this paper: background citation

Exploration of Diagnosis and Treatment Strategies and Prognostic Prediction Models for Acute Respiratory Distress Syndrome Based on Radiographic Evaluations Assessed by Artificial Intelligence

TypeobservationalSponsorShanghai Zhongshan HospitalRan2024 to 2025Enrolled400ConditionsARDS (Acute Respiratory Distress Syndrome), AI (Artificial Intelligence)ArmsCT scan
3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 44 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Lung Imaging and Artificial Intelligence in ARDS.Journal of clinical medicine · 2024
    Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. Continuous Lower Abdominal Compression as a Therapeutic Intervention in COVID-19 ARDS.Clinical medicine insights. Circulatory, respiratory and pulmonary medicine · 2021
    Article
  14. Article
  15. Article
  16. Tailoring the cure: still science fiction?Journal of thoracic disease · 2019
    Article
  17. Article
  18. Article
  19. Article
  20. Lung imaging: how to get better look inside the lung.Annals of translational medicine · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Davide ChiumelloDipartimento di Anestesia, Rianimazione (Intensiva e Subintensiva) e Terapia del Dolore, Fondazione IRCCS Ca' Granda-Ospedale Maggiore Policlinico, Via Francesco Sforza 35, 20122, Milan, Italy. chiumello@libero.it
Antonella Marino
Matteo Brioni
Federica Menga
Irene Cigada
Marco Lazzerini
Maria C Andrisani
Pietro Biondetti
Bruno Cesana
Luciano Gattinoni
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITUniversity of Milan · ITUniversity of Brescia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe computation of lung recruitability in acute respiratory distress syndrome (ARDS) is advocated to set positive end-expiratory pressure (PEEP) for preventing lung collapse. The quantitative lung CT scan, obtained by manual image processing, is the reference method but it is time consuming. The aim of this study was to evaluate the accuracy of a visual anatomical analysis compared with a quantitative lung CT scan analysis in assessing lung recruitability.

methodsFifty sets of two complete lung CT scans of ALI/ARDS patients computing lung recruitment were analyzed. Lung recruitability computed at an airway pressure of 5 and 45 cm H(2)O was defined as the percentage decrease in the collapsed/consolidated lung parenchyma assessed by two expert radiologists using a visual anatomical analysis and as the decrease in not aerated lung regions using a quantitative analysis computed by dedicated software.

resultsLung recruitability was 11.3 % (interquartile range 7.39-16.41) and 15.5 % (interquartile range 8.18-21.43) with the visual anatomical and quantitative analysis, respectively. In the Bland-Altman analysis, the bias and agreement bands between the visual anatomical and quantitative analysis were -2.9 % (-11.8 to +5.9 %). The ROC curve showed that the optimal cutoff values for the visual anatomical analysis in predicting high versus low lung recruitability was 8.9 % (area under the ROC curve 0.9248, 95 % CI 0.8550-0.9946). Considering this cutoff, the sensitivity, specificity, and diagnostic accuracy were 0.96, 0.76, and 0.86, respectively.

conclusionsVisual anatomical analysis can classify patients into those with high and low lung recruitability allowing more intensivists to get access to lung recruitability assessment.

Indexed as

Tomography, X-Ray ComputedAcute Lung InjuryFemaleHumansLungMaleMiddle AgedPositive-Pressure RespirationRespiration, ArtificialRespiratory Distress SyndromeSensitivity and Specificity

Identifiers

PMID22990871
OpenAlexW2059281724

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.