Evidence map›Paper›PMID 22990216›Full record

Trial reportNicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco2013

Impact of smoking exposure change on infant birth weight among a cohort of women in a prenatal smoking cessation study.

Ruby Benjamin-Garner, Angela Stotts

Open access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 31 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Effects of Tobacco Consumption and Anxiety or Depression during Pregnancy on Maternal and Neonatal Health.International journal of environmental research and public health · 2020
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Cigarette Smoking During Pregnancy: Do Complete Abstinence and Low Level Cigarette Smoking Have Similar Impact on Birth Weight?Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2017
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Missouri Mothers and Their Children: A Family Study of the Effects of Genetics and the Prenatal Environment.Twin research and human genetics : the official journal of the International Society for Twin Studies · 2015
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Ruby Benjamin-GarnerCenter for Clinical and Translational Sciences, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA. Ruby.A.Benjamin-Garner@uth.tmc.edu
Angela Stotts
The University of Texas Health Science Center at Houston · USThe University of Texas System · US

Funding

U OF TEXAS HLTH SCI CTR HOUSTON CENTER FOR CLINICAL AND TRANSLATIONAL SCIENCESUL1RR024148 · NCRR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MCPHERSON, DAVID D · 2006 to 2010
$27.9M
Zolmitriptan challenge and human performance testingM01RR002558 · NCRR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI SCHULTZ, STANLEY G · 1985 to 2006
$10.3M
NCRR NIH HHS M01 RR002558NCRR NIH HHS M01RR02558NCRR NIH HHS UL1 RR024148NCRR NIH HHS UL1RR024148
6 · The paper itself

Abstract

introductionDespite the known harmful effects of smoking during pregnancy, the highly addicted find it difficult to quit. Decreased smoking may be regarded as a means of harm reduction. There is limited information on the benefits of smoking reduction short of quitting. This study used salivary cotinine to assess the impact of change in smoking exposure on birth weight in full-term infants.

methodsIn a prenatal smoking cessation study, smoking status was validated by saliva cotinine at baseline and end of pregnancy (EOP). Salivary cotinine ≥15 ng/ml defined active smoking. Based on salivary cotinine, women were grouped as nonsmoking/quit, light exposure (<150 ng/ml), and heavy exposure (≥150 ng/ml) at baseline and EOP. EOP and baseline smoking status were stratified to form smoking exposure change groups. Mean birth weight was compared among those who quit, reduced, maintained, and increased.

resultsSmoking cessation was associated with a 299 g increase in birth weight compared with sustained heavy smoking, p = .021. Reduced exposure from heavy to light was associated with a 199 g increase in birth weight compared with sustained heavy exposure, a 103 g increase compared with increased exposure, and a 63 g increase compared with sustained light exposure. Differences among continuing smokers were not statistically significant.

conclusionsAlthough not statistically significant, the increase in infant birth weight associated with reduction from heavy to light exposure suggests potential for benefit. The only statistically significant comparison was between quitters and sustained heavy smokers, confirming that smoking cessation should remain the goal for pregnant women.

Indexed as

AdolescentAdultBirth WeightCohort StudiesCotinineFemaleHarm ReductionHumansInfantMaternal ExposurePregnancySalivaSelf ReportSmokingSmoking CessationTexasCotinine

Identifiers

PMID22990216
PMCPMC3611991
OpenAlexW2124961493

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.