Evidence map›Paper›PMID 22990212›Full record

ReviewNicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco2012

Nicotinic regulation of energy homeostasis.

Michele Zoli, Marina R Picciotto

Open access · greenAbstract readReview
In one paragraph

Review in Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 80 citations in OpenAlex.

  1. Differential Efficacy of Nicotine Replacement Among Overweight and Obese Women Smokers.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2015
    Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Sex-Dependent Effects of Inhaled Nicotine on the Gut Microbiome.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2022
    Article
  10. Article
  11. Article
  12. Sex differences in factors associated with prediabetes in Korean adults.Osong public health and research perspectives · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Nicotinic Acetylcholine Receptor Signaling in the Hypothalamus: Mechanisms Related to Nicotine's Effects on Food Intake.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2020
    Review
  18. Profound alteration in reward processing due to a human polymorphism in CHRNA5: a role in alcohol dependence and feeding behavior.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2019
    Article
  19. Does everyone who quit smoking gain weight? A real-world prospective cohort study.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2019
    Article
  20. The impact of tobacco smoking on physical activity and metabolism in mice.International journal of molecular epidemiology and genetics · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Michele ZoliDepartment of Biomedical, Metabolic, and Neural Sciences, University of Modena and Reggio Emilia, Via Campi 287, 41125, Modena, Italy. michele.zoli@unimore.it
Marina R Picciotto
Policlinico di Modena · ITYale University · US

Funding

Anatomical basis for nicotine addiction in miceR01DA014241 · NIDA · YALE UNIVERSITY · PI PICCIOTTO, MARINA R · 2001 to 2018
$5.2M
Anatomical Basis for Nicotine AddictionR37DA014241 · NIDA · YALE UNIVERSITY · PI Marina R Picciotto · 2020 to 2026
$2.7M
NIDA NIH HHS DA14241NIDA NIH HHS R01 DA014241NIDA NIH HHS R37 DA014241
6 · The paper itself

Abstract

introductionThe ability of nicotine, the primary psychoactive substance in tobacco smoke, to regulate appetite and body weight is one of the factors cited by smokers that prevents them from quitting and is the primary reason for smoking initiation in teenage girls. The regulation of feeding and metabolism by nicotine is complex, and recent studies have begun to identify nicotinic acetylcholine receptor (nAChR) subtypes and circuits or cell types involved in this regulation. DISCUSSION: We will briefly describe the primary anatomical and functional features of the input, output, and central integration structures of the neuroendocrine systems that regulate energy homeostasis. Then, we will describe the nAChR subtypes expressed in these structures in mammals to identify the possible molecular targets for nicotine. Finally, we will review the effects of nicotine and its withdrawal on feeding and energy metabolism and attribute them to potential central and peripheral cellular targets.

Indexed as

Adipose TissueAnimalsAutonomic Nervous SystemBody WeightEnergy MetabolismEnteric Nervous SystemFoodHomeostasisHumansNeuronsNicotineReceptors, NicotinicSmoking CessationTobacco Use DisorderNicotineReceptors, Nicotinic

Identifiers

PMID22990212
PMCPMC3611985
OpenAlexW2163162175

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.