Evidence map›Paper›PMID 22988042›Full record

Trial reportPalliative medicine2013

Communicating advanced cancer patients' symptoms via the Internet: a pooled analysis of two randomized trials examining caregiver preparedness, physical burden, and negative mood.

Ming-Yuan Chih, Lori L DuBenske, Robert P Hawkins, Roger L Brown, Susan K Dinauer, James F Cleary, David H Gustafson

2 registry-linked trialsAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Palliative medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 37 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 9 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00214162 nacompletednot on this map

Web-based Support for Informal Caregivers in Cancer

TypeinterventionalSponsorUniversity of Wisconsin, MadisonRan2004 to 2008Enrolled235ConditionsBreast Cancer, Prostate CancerArmsComprehensive Health Enhancement Support System, computer with internet
NCT00365963 phase3completednot on this map

Clinician Integration Study

TypeinterventionalSponsorUniversity of Wisconsin, MadisonRan2005 to 2007Enrolled284ConditionsNon-Small Cell Lung CancerArmsComprehensive Health Enhancement Support System
3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 9 syntheses or guidelines pooled it.

  1. Pooled it
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  10. Empowering caregivers in the radiotherapy process: the results of a randomized controlled trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Trial
  11. Trial
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  14. Technology-based applications for relatives and caregivers of people with advanced breast cancer-a scoping review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  15. Article
  16. Review
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  18. Observational
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  20. Caregivers' demands: caring atmosphere expected by cancer patients' caregivers-a qualitative content analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ming-Yuan ChihDepartment of Industrial and Systems Engineering, University of Wisconsin-Madison, Madison, WI, USA. chih@uwalumni.com
Lori L DuBenske
Robert P Hawkins
Roger L Brown
Susan K Dinauer
James F Cleary
David H Gustafson

Funding

Using Technology to Enhance Cancer Communication and Improve Clinical OutcomesP50CA095817 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI GUSTAFSON, DAVID H · 2003 to 2012
$19.3M
Web-Based Support for Informal Caregivers in CancerR01NR008260 · NINR · UNIVERSITY OF WISCONSIN-MADISON · PI GUSTAFSON, DAVID H · 2002 to 2006
$2.3M
NCI NIH HHS 1 P50 CA095817-01A1NCI NIH HHS P50 CA095817NINR NIH HHS R01 NR008260NINR NIH HHS R01 NR008260-01
6 · The paper itself

Abstract

backgroundUsing available communication technologies, clinicians may offer timely support to family caregivers in managing symptoms in patients with advanced cancer at home.

aimTo assess the effects of an online symptom reporting system on caregiver preparedness, physical burden, and negative mood.

designA pooled analysis of two randomized trials (NCT00214162 and NCT00365963) was conducted to compare caregiver outcomes at 6 and 12 months after intervention between two randomized, unblinded groups using General Linear Mixed Modeling. Caregivers in one group (Comprehensive Health Enhancement Support System-Only) were given access to an interactive cancer communication system, the Comprehensive Health Enhancement Support System. Those in the other group (Comprehensive Health Enhancement Support System + Clinician Report) received access to Comprehensive Health Enhancement Support System plus an online symptom reporting system called the Clinician Report. Clinicians of patients in the Comprehensive Health Enhancement Support System + Clinician Report group received e-mail alerts notifying them when a symptom distress was reported over a predetermined threshold. SETTING/

participantsDyads (n = 235) of advanced-stage lung, breast, and prostate cancer patients and their adult caregivers were recruited at five outpatient oncology clinics in the United States.

resultsCaregivers in the Comprehensive Health Enhancement Support System + Clinician Report group reported less negative mood than those in the Comprehensive Health Enhancement Support System-Only group at both 6 months (p = 0.009) and 12 months (p = 0.004). Groups were not significantly different on caregiver preparedness or physical burden at either time point.

conclusionsThis study provides new evidence that by using an online symptom reporting system, caregivers may experience less emotional distress due to the Clinician Report's timely communication of caregiving needs in symptom management to clinicians.

Indexed as

InternetAdaptation, PsychologicalAdultAffectAgedBreast NeoplasmsCaregiversCommunicationCost of IllnessFemaleHumansLinear ModelsLung NeoplasmsMaleMiddle AgedPalliative CarecancerCaregiverscommunication barrierseHealthpalliative caresigns and symptoms

Identifiers

PMID22988042
PMCPMC3819140

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.