Evidence map›Paper›PMID 22987795›Full record

ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2013

Associations between arterial elasticity and markers of inflammation in healthy older women.

Gordon Fisher, Gary R Hunter, Stephen P Glasser

Open access · bronzeAbstract read
In one paragraph

Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Associations of Heart Rate With Inflammatory Markers Are Modulated by Gender and Obesity in Older Adults.The journals of gerontology. Series A, Biological sciences and medical sciences · 2015
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Gordon FisherDepartment of Nutrition Sciences, University of Alabama at Birmingham, 427 Webb Building, 1675 University Blvd, Birmingham, AL 35294-3360, USA. grdnfs@uab.edu
Gary R Hunter
Stephen P Glasser
Nutrition Sciences (Belgium) · BEUniversity of Alabama at Birmingham · US

Funding

Why is the prevalence of obesity so high in U.S. Southern States? Regional predictors of BMI and obesity treatment response.P30DK056336 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI James O Hill · 2000 to 2026
$31.9M
University of Alabama at Birmingham's Diabetes Research CenterP30DK079626 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Kirk Michael Habegger · 2013 to 2026
$19.5M
UAB Obesity Training ProgramT32DK062710 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI James O Hill, Brooks C Wingo · 2004 to 2026
$5.5M
Frequency of aerobic/resistance training in older womenR01AG027084 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI HUNTER, GARY R · 2005 to 2009
$1.6M
NIA NIH HHS R01AG027084-01NIDDK NIH HHS P30 DK056336NIDDK NIH HHS P30 DK079626NIDDK NIH HHS P30-DK56336NIDDK NIH HHS T32 DK062710NIDDK NIH HHS T32DK062710-07
6 · The paper itself

Abstract

The purpose of this investigation was to examine the associations between circulating markers of inflammation and arterial elasticity in healthy older women. Participants were 50 women older than 60 years of age, body mass index 27 ± 4, and physically untrained. Large artery elasticity, small artery elasticity, systemic vascular resistance, total vascular impedance, estimated cardiac output, and estimated cardiac index were determined using pulse contour analysis. Serum concentrations of tumor necrosis factor-α, C-reactive protein (CRP), and interleukin 6 were assessed. Results from Pearson's correlation revealed that tumor necrosis factor-α was inversely associated with large artery elasticity (-.426, p < .01) and estimated cardiac index (-.324, p < .05) and positively associated with systemic vascular resistance (.386, p < .01) and total vascular impedance (.416, p < .01). Additionally, C-reactive protein was inversely associated with large artery elasticity (-.308, p < .01). The overall implication was that tumor necrosis factor-α and C-reactive protein appear to be critical inflammatory cytokines associated with reductions in arterial elasticity in older women.

Indexed as

AgedArteriesBiomarkersBody Mass IndexC-Reactive ProteinCross-Sectional StudiesElasticityFemaleHeart Function TestsHemorheologyHumansInflammationInterleukin-6Middle AgedTumor Necrosis Factor-alphaVascular ResistanceBiomarkersC-Reactive ProteinInterleukin-6Tumor Necrosis Factor-alpha

Identifiers

PMID22987795
PMCPMC3593615
OpenAlexW2135924555

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.