Evidence map›Paper›PMID 22987309›Full record

ReviewJournal of cardiovascular translational research2012

Cardiac myocyte-fibroblast interactions and the coronary vasculature.

Stephanie L K Bowers, Troy A Baudino

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of cardiovascular translational research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Extracellular Matrix in Regulation of Contractile System in Cardiomyocytes.International journal of molecular sciences · 2019
    Review
  5. Article
  6. Article
  7. Cellular Communications in the Heart.Cardiac failure review · 2015
    Article
  8. Aging, exercise, and extracellular matrix in the heart.Journal of exercise rehabilitation · 2013
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Stephanie L K BowersTexas A&M Health Science Center, Cardiovascular Research Institute, 1901 South First St., Bldg 205, Temple, TX 76504, USA.
Troy A Baudino

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Treatment of cardiovascular diseases relies on the ability not only to abrogate and compensate for congenital deformities but also to repair cardiac pathologies in the adult. Determining how cells communicate within the myocardium and how to use this communication to repair and treat pathological conditions have been necessary steps in the successful intervention of cardiac diseases. In this regard, research has mostly focused on relationships between the main cellular constituents of the heart, myocytes, and fibroblasts. However, the coronary vasculature is also critical to myocardial organization and integrity, and how the vasculature influences and responds to cues from cardiac myocytes and fibroblasts is largely underappreciated. This review discusses how factors that affect myocyte and fibroblast physiology and communication may also interact with the coronary vasculature. Defining the mechanisms of these cellular relationships will help identify ways to control angiogenesis during cardiac remodeling and the development of tissue-engineered therapies.

Indexed as

Cell CommunicationAnimalsCoronary VesselsFibroblastsFibrosisHeart DiseasesHumansMyocytes, CardiacNeovascularization, PhysiologicRegenerationSignal TransductionTissue Engineering

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.