Evidence map›Paper›PMID 22986022›Full record

ArticleBiochimie2013

Shotgun cholanomics of ileal fluid.

Yingjie Chen, Michael Ogundare, Christopher M Williams, Yuchen Wang, Yuqin Wang, Gavin W Sewell, Philip J Smith, Farooq Z Rahman, Nuala O'Shea, Anthony W Segal and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Biochimie, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Yingjie ChenClinical Laboratory, The Second Hospital of Shandong University, Jinan, China.
Michael Ogundare
Christopher M Williams
Yuchen Wang
Yuqin Wang
Gavin W Sewell
Philip J Smith
Farooq Z Rahman
Nuala O'Shea
Anthony W Segal
William J Griffiths
University College London · GBJinan Infectious Disease Hospital · CNShandong University · CNSwansea University · GB

Funding

Biotechnology and Biological Sciences Research Council BB/C511356/1Biotechnology and Biological Sciences Research Council BBC5113561Biotechnology and Biological Sciences Research Council BB/C515771/2Biotechnology and Biological Sciences Research Council BBC5157712Biotechnology and Biological Sciences Research Council BB/H001018/1Biotechnology and Biological Sciences Research Council BBH0010181Biotechnology and Biological Sciences Research Council BBI0017351Department of Health 482Medical Research Council G0902005Medical Research Council G0902022Wellcome Trust 088683
6 · The paper itself

Abstract

In this study we have developed a rapid method for the shotgun analysis of bile acids in intestinal fluid. The method is semi-quantitative, and requires little sample preparation. Bile salts might contribute to the pathogenesis of Crohn's disease. In a pilot study we demonstrate the method by analysing the bile acid content of ileal fluid from seven Crohn's disease patients and three healthy controls. The dominant bile acids observed were di and/or trihydroxycholanoates, di- and/or trihydroxycholanoylglycines, di- and/or tri-hydroxycholanoyltaurines, monosulphated dihydroxycholanoates and monosulphated dihydroxycholanoylglycine. The method can be similarly applied to samples derived from other parts of the intestine.

Indexed as

Bile Acids and SaltsBody FluidsCase-Control StudiesCrohn DiseaseHumansIleumMass SpectrometryBile Acids and Salts

Identifiers

PMID22986022
PMCPMC4529479
OpenAlexW2034118111

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.