ReviewSeminars in pediatric surgery2012
Hirschsprung-associated enterocolitis: prevention and therapy.
Review in Seminars in pediatric surgery, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02193685 (Identification of Genetic, Immunologic and Microbial Markers of Hirschsprung Associated Enterocolitis in Children With Hirschsprung Disease), which is not on this map. Cited by 58 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Identification of Genetic, Immunologic and Microbial Markers of Hirschsprung Associated Enterocolitis in Children With Hirschsprung Disease
Who cites it
58 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Updated European Reference Network for rare Inherited and Congenital Digestive and Gastrointestinal Anomalies guidelines for the management of rectosigmoid Hirschsprung's disease 2025.Journal of pediatric gastroenterology and nutrition · 2026Guideline
- Prevalence of Hirschsprung-associated enterocolitis in patients with Hirschsprung disease.Pediatric surgery international · 2022Pooled it
- Management and outcomes for long-segment Hirschsprung disease: A systematic review from the APSA Outcomes and Evidence Based Practice Committee.Journal of pediatric surgery · 2021Pooled it
- The impact of Clostridium difficile on paediatric surgical practice: a systematic review.Pediatric surgery international · 2014Pooled it
- Cholinergic Signaling Attenuates Pro-Inflammatory Interleukin-8 Response in Colonic Epithelial Cells.Frontiers in immunology · 2021Trial
- Altered fecal short chain fatty acid composition in children with a history of Hirschsprung-associated enterocolitis.Journal of pediatric surgery · 2016Trial
- Probiotics prevent Hirschsprung's disease-associated enterocolitis: a prospective multicenter randomized controlled trial.International journal of colorectal disease · 2015Trial
- Gastrointestinal symptoms and association to food items in children with hirschsprung disease: a multinational patient-reported outcome study from Latin America and Spain.Pediatric surgery international · 2026Article
- Article
- Surgical decision making in late-presenting Hirschsprung's disease: direct pull-though or stoma first.Frontiers in surgery · 2026Review
- Microbiota decolonization of bacterial pathogens in pediatric surgery-related intestinal disorders: Insights on current strategies and future outlook.World journal of clinical pediatrics · 2025Review
- Impairment of stromal-epithelial regenerative cross-talk in Hirschsprung disease primes for the progression to enterocolitis.Science translational medicine · 2025Article
- Integrated quantitative proteomics and phosphoproteomics analysis reveals USP46-POU4F1-HPSE signaling axis in the pathogenesis of Hirschsprung disease.Acta biochimica et biophysica Sinica · 2025Article
- Development of a nomogram for predicting postoperative Hirschsprung-associated enterocolitis.Frontiers in pediatrics · 2025Article
- Article
- Early Detection and Intervention for Hirschsprung's Disease: A Key to Successful Outcomes.Clinical medicine insights. Case reports · 2024Article
- Hirschsprung-associated enterocolitis: a comprehensive review.World journal of pediatric surgery · 2024Review
- Hirschsprung's disease associated enterocolitis: A comprehensive review.World journal of clinical pediatrics · 2023Review
- Rare presentation and retrograde diagnosis of total colonic aganglionosis in a female infant: a case report.Journal of medical case reports · 2023Article
- Prognostic factors of postoperative Hirschsprung-associated enterocolitis: a cohort study.Pediatric surgery international · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Hirschsprung-associated enterocolitis remains the greatest cause of morbidity and mortality in children with Hirschsprung disease. This chapter details the various approaches used to treat and prevent this disease process. This includes prevention of complications, such as stricture formation, prophylaxis with rectal washouts, and identification of high-risk individuals. The chapter also details approaches to diagnose Hirschsprung-associated enterocolitis as well as to exclude other etiologies.
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.