Evidence map›Paper›PMID 22985781›Full record

ReviewMicrobes and infection2012

Innate immune responses to Chlamydia pneumoniae infection: role of TLRs, NLRs, and the inflammasome.

Kenichi Shimada, Timothy R Crother, Moshe Arditi

Abstract readReview
In one paragraph

Review in Microbes and infection, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Review
  2. Article
  3. Identification of KeyInternational journal of molecular sciences · 2023
    Article
  4. Review
  5. Microbial cell (Graz, Austria) · 2019
    Article
  6. Article
  7. Article
  8. Bacteria-Host Interactions in Multiple Sclerosis.Frontiers in microbiology · 2018
    Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Chlamydia cell biology and pathogenesis.Nature reviews. Microbiology · 2016
    Review
  16. Forum on immunopathological diseases and therapeutics · 2016
    Article
  17. Article
  18. Article
  19. Article
  20. Old, new and emerging functions of caspases.Cell death and differentiation · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kenichi ShimadaDivision of Pediatric Infectious Diseases and Immunology, Cedars-Sinai Medical Center and David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA 90048, USA.
Timothy R Crother
Moshe Arditi

Funding

MOLECULAR PATHOGENESIS OF CHLAMYDIA-INDUCED ATHEROGENESIR01HL066436 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI ARDITI, MOSHE · 2001 to 2013
$3.6M
Role of Innate Immunity in Pathogenesis of Chlamydia Pneumonia InfectionR01AI067995 · NIAID · CEDARS-SINAI MEDICAL CENTER · PI ARDITI, MOSHE · 2006 to 2010
$1.9M
Innate Immunity and Host Responses in Pathogenesis of Chlamydia PneumoniaeR56AI067995 · NIAID · CEDARS-SINAI MEDICAL CENTER · PI ARDITI, MOSHE · 2012 to 2012
$413k
NHLBI NIH HHS HL-66436NHLBI NIH HHS R01 HL066436NIAID NIH HHS AI-067995NIAID NIH HHS R01 AI067995NIAID NIH HHS R56 AI067995
6 · The paper itself

Abstract

Chlamydiae are important human pathogens that are responsible for a wide rage of diseases with a significant impact on public health. In this review article we highlight how recent studies have increased our knowledge of Chlamydia pneumoniae pathogenesis and mechanisms of innate immunity directed host defense against C. pneumoniae infection.

Indexed as

AnimalsChlamydia InfectionsChlamydophila pneumoniaeHumansImmunity, InnateInflammasomesReceptors, Cytoplasmic and NuclearToll-Like ReceptorsVascular DiseasesInflammasomesReceptors, Cytoplasmic and NuclearToll-Like Receptors

Identifiers

PMID22985781
PMCPMC3511600

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.