Trial reportInternational wound journal2014
Manuka honey-impregnated dressings in the treatment of neuropathic diabetic foot ulcers.
Trial report in International wound journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 10 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
49 citing papers in PubMed, 10 syntheses or guidelines pooled it, 133 citations in OpenAlex.
- Clinical Evidence of Traditional Medicines in Modulating the Immune Response and Diabetic Wound Healing.Current topics in medicinal chemistry · 2026Pooled it
- Honey dressing for diabetic foot ulcers: a systematic review and meta-analysis of randomized controlled trials.Frontiers in endocrinology · 2026Pooled it
- The efficacy of three antimicrobial dressings in the management of diabetic foot ulcers: a systematic review and network meta-analysis.Frontiers in endocrinology · 2026Pooled it
- Efficacy and Safety of Biomaterials and Antimicrobial Dressings in the Treatment of Diabetic Foot Ulcers: A Systematic Review and Network Meta-Analysis.Journal of diabetes research · 2025Pooled it
- Pooled it
- Efficacy and Safety of Honey Dressings in the Management of Chronic Wounds: An Updated Systematic Review and Meta-Analysis.Nutrients · 2024Pooled it
- Effect of honey dressing in the management of diabetic foot ulcers: A meta-analysis.International wound journal · 2023Pooled it
- A Net Meta-Analysis of the Effectiveness of Different Types of Dressings in the Treatment of Diabetic Foot.Computational and mathematical methods in medicine · 2022Pooled it
- Topical antimicrobial agents for treating foot ulcers in people with diabetes.The Cochrane database of systematic reviews · 2017Pooled it
- Honey as a topical treatment for wounds.The Cochrane database of systematic reviews · 2015Pooled it
- Clinical and Postoperative Applications of Manuka Honey in Wound Healing: An Evidence-Based Review.International wound journal · 2026Review
- Manuka honey as a natural remedy for diabetic foot ulcers: efficacy compared with silver-based dressing.Frontiers in pharmacology · 2026Article
- Advancement in nanocarrier-mediated delivery of herbal bioactives: from bench to beside.Natural products and bioprospecting · 2025Review
- Medical-grade honey as treatment for udder cleft dermatitis in dairy cows.JDS communications · 2025Article
- In Vitro Evidence for the Efficacy of Manuka Honey and Its Components Against the Major Human PathogenicPharmaceuticals (Basel, Switzerland) · 2025Article
- Topical Application of Manuka Honey for the Treatment of Non-Healing Venous Leg Ulcers.Pharmaceuticals (Basel, Switzerland) · 2025Article
- Unlocking the Healing Potential: A Comprehensive Review of Ecology and Biology of Medical-Grade Honey in Wound Management and Tissue Regeneration.Health science reports · 2025Article
- Unlocking the potential of flavonoid-infused drug delivery systems for diabetic wound healing with a mechanistic exploration.Inflammopharmacology · 2024Review
- Anti-Inflammatory and Wound Healing Properties of Different Honey Varieties from Romania and Correlations to Their Composition.Life (Basel, Switzerland) · 2024Article
- Wound pH-Modulating Strategies for Diabetic Wound Healing.Advances in wound care · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this study, we investigate the effect of manuka honey-impregnated dressings (MHID) on the healing of neuropathic diabetic foot ulcers (NDFU). A total of 63 Caucasians, type 2 diabetic patients followed up in the diabetic foot outpatient clinic comprised the study population. Patients were randomised in two groups as follows: group I patients were treated with MHID and group II patients were treated with conventional dressings (CD). The patients were followed up on a weekly basis for 16 weeks. Mean healing time was 31 ± 4 days in group I versus 43 ± 3 days in group II (P < 0·05). In group I patients 78·13% of ulcers became sterile during the first week versus 35·5% in group II patients; the corresponding percentages for weeks 2, 4 and 6 were 15·62% versus 38·7%, 6·25% versus 12·9% and 0% versus 12·9% respectively. The percent of ulcers healed did not differ significantly between groups (97% for MHID and 90% for CD). MHID represent an effective treatment for NDFU leading to a significant reduction in the time of healing and rapid disinfection of ulcers.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.