Trial reportJournal of the American Geriatrics Society2012
Enhanced fitness: a randomized controlled trial of the effects of home-based physical activity counseling on glycemic control in older adults with prediabetes mellitus.
Trial report in Journal of the American Geriatrics Society, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00594399 (Enhancing Fitness in Older Overweight Vets With Impaired Fasting Glucose), which is not on this map. Cited by 19 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Enhancing Fitness in Older Overweight Vets With Impaired Fasting Glucose
Who cites it
19 citing papers in PubMed, 6 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- Effects of different exercise types on visceral adipose tissue and glycemic parameters in adults with stage 1 cardiovascular-kidney-metabolic syndrome: a systematic review and network meta-analysis of randomized controlled trials.Frontiers in cardiovascular medicine · 2026Pooled it
- Effectiveness of physical activity interventions delivered or prompted by health professionals in primary care settings: systematic review and meta-analysis of randomised controlled trials.BMJ (Clinical research ed.) · 2022Pooled it
- The Effect of Physical Activity Interventions on Glycosylated Haemoglobin (HbASports medicine (Auckland, N.Z.) · 2018Pooled it
- Automated telephone communication systems for preventive healthcare and management of long-term conditions.The Cochrane database of systematic reviews · 2016Pooled it
- Interactive telemedicine: effects on professional practice and health care outcomes.The Cochrane database of systematic reviews · 2015Pooled it
- Effects of Exercise Training on Cardiorespiratory Fitness and Biomarkers of Cardiometabolic Health: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Journal of the American Heart Association · 2015Pooled it
- Intervention Mapping: A Framework to Co-Design the ALAPAGE Programme to Simultaneously Improve Dietary Diversity and Physical Fitness Among Older People.Health expectations : an international journal of public participation in health care and health policy · 2026Trial
- Endothelial Progenitor Cell Levels Predict Future Physical Function: An Exploratory Analysis From the VA Enhanced Fitness Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2016Trial
- PTSD is negatively associated with physical performance and physical function in older overweight military Veterans.Journal of rehabilitation research and development · 2014Trial
- Lower levels of circulating progenitor cells are associated with low physical function and performance in elderly men with impaired glucose tolerance: a pilot substudy from the VA Enhanced Fitness trial.The journals of gerontology. Series A, Biological sciences and medical sciences · 2013Trial
- Modifiable determinants of older adults' physical activity and sedentary behavior in community and healthcare settings: a DE-PASS systematic review and meta-analysis.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2025Article
- Article
- Determining Physical Activity Characteristics from Wristband Data for Use in Automated Insulin Delivery Systems.IEEE sensors journal · 2020Article
- Physical Activity and Related Psychosocial Outcomes From a Pilot Randomized Trial of an Interactive Voice Response System-Supported Intervention in the Deep South.Health education & behavior : the official publication of the Society for Public Health Education · 2018Article
- Observational
- Physical Activity Counseling Promotes Physical and Psychological Resilience in Older Veterans with Posttraumatic Stress Disorder.Mental health and physical activity · 2016Article
- A Novel Analytic Technique to Measure Associations Between Circulating Biomarkers and Physical Performance Across the Adult Life Span.The journals of gerontology. Series A, Biological sciences and medical sciences · 2016Article
- Treatment for overweight and obesity in adult populations: a systematic review and meta-analysis.CMAJ open · 2014Article
- Depletion of circulating progenitor cells precedes overt diabetes: a substudy from the VA enhanced fitness trial.Journal of diabetes and its complicationsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 6 institutions in 1 country.
Funding
Abstract
objectivesTo determine whether a home-based multicomponent physical activity counseling (PAC) intervention is effective in reducing glycemic measures in older outpatients with prediabetes mellitus.
designControlled clinical trial.
settingPrimary care clinics of the Durham Veterans Affairs (VA) Medical Center between September 29, 2008, and March 25, 2010.
participantsThree hundred two overweight (body mass index 25-45 kg/m(2) ), older (60-89) outpatients with impaired glucose tolerance (fasting blood glucose 100-125 mg/dL, glycosylated hemoglobin (HbA1c) <7%) randomly assigned to a PAC intervention group (n = 180) or a usual care control group (n = 122).
interventionA 12-month, home-based multicomponent PAC program including one in-person baseline counseling session, regular telephone counseling, physician endorsement in clinic with monthly automated encouragement, and customized mailed materials. All study participants, including controls, received a consultation in a VA weight management program. MEASUREMENTS: The primary outcome was a homeostasis model assessment of insulin resistance (HOMA-IR), calculated from fasting insulin and glucose levels at baseline and 3 and 12 months. HbA1c was the secondary indicator of glycemic control. Other secondary outcomes were anthropometric measures and self-reported physical activity, health-related quality of life, and physical function.
resultsThere were no significant differences between the PAC and control groups over time for any of the glycemic indicators. Both groups had small declines over time of approximately 6% in fasting blood glucose (P < .001), and other glycemic indicators remained stable. The declines in glucose were not sufficient to affect the change in HOMA-IR scores due to fluctuations in insulin over time. Endurance physical activity increased significantly in the PAC group (P < .001) and not in the usual care group.
conclusionHome-based telephone counseling increased physical activity levels but was insufficient to improve glycemic indicators in older outpatients with prediabetes mellitus.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.