Evidence map›Paper›PMID 22984483›Full record

ArticlePloS one2012

Why most biomedical findings echoed by newspapers turn out to be false: the case of attention deficit hyperactivity disorder.

François Gonon, Jan-Pieter Konsman, David Cohen, Thomas Boraud

Abstract read
In one paragraph

Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. A biased ADHD discourse ignores human uniqueness.International journal of qualitative studies on health and well-being · 2017
    Article
  11. Article
  12. How French media have portrayed ADHD to the lay public and to social workers.International journal of qualitative studies on health and well-being · 2017
    Article
  13. Article
  14. Review
  15. Evidence-Based Practice: Separating Science From Pseudoscience.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2015
    Review
  16. Article
  17. Article
  18. Shooting the Messenger: The Case of ADHD.Journal of contemporary psychotherapy · 2014
    Article
  19. Article
  20. Deep impact: unintended consequences of journal rank.Frontiers in human neuroscience · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

François GononInstitute of Neurodegenerative Diseases, University of Bordeaux, Bordeaux, France. francois.gonon@u-bordeaux2.fr
Jan-Pieter Konsman
David Cohen
Thomas Boraud

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextBecause positive biomedical observations are more often published than those reporting no effect, initial observations are often refuted or attenuated by subsequent studies.

objectiveTo determine whether newspapers preferentially report on initial findings and whether they also report on subsequent studies.

methodsWe focused on attention deficit hyperactivity disorder (ADHD). Using Factiva and PubMed databases, we identified 47 scientific publications on ADHD published in the 1990s and soon echoed by 347 newspapers articles. We selected the ten most echoed publications and collected all their relevant subsequent studies until 2011. We checked whether findings reported in each "top 10" publication were consistent with previous and subsequent observations. We also compared the newspaper coverage of the "top 10" publications to that of their related scientific studies.

resultsSeven of the "top 10" publications were initial studies and the conclusions in six of them were either refuted or strongly attenuated subsequently. The seventh was not confirmed or refuted, but its main conclusion appears unlikely. Among the three "top 10" that were not initial studies, two were confirmed subsequently and the third was attenuated. The newspaper coverage of the "top 10" publications (223 articles) was much larger than that of the 67 related studies (57 articles). Moreover, only one of the latter newspaper articles reported that the corresponding "top 10" finding had been attenuated. The average impact factor of the scientific journals publishing studies echoed by newspapers (17.1 n = 56) was higher (p<0.0001) than that corresponding to related publications that were not echoed (6.4 n = 56).

conclusionBecause newspapers preferentially echo initial ADHD findings appearing in prominent journals, they report on uncertain findings that are often refuted or attenuated by subsequent studies. If this media reporting bias generalizes to health sciences, it represents a major cause of distortion in health science communication.

Indexed as

Biomedical ResearchNewspapers as TopicAttention Deficit Disorder with HyperactivityCommunications MediaDopamine Plasma Membrane Transport ProteinsGenetic Predisposition to DiseaseHumansJournal Impact FactorMeta-Analysis as TopicReceptors, Dopamine D4Substance-Related DisordersUniversitiesDopamine Plasma Membrane Transport ProteinsDRD4 protein, humanReceptors, Dopamine D4

Identifiers

PMID22984483
PMCPMC3440402

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.