Evidence map›Paper›PMID 22984118›Full record

ArticleThe Journal of infectious diseases2012

Influenza and malaria coinfection among young children in western Kenya, 2009-2011.

Mark G Thompson, Robert F Breiman, Mary J Hamel, Meghna Desai, Gideon Emukule, Sammy Khagayi, David K Shay, Kathleen Morales, Simon Kariuki, Godfrey M Bigogo and 6 more

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of infectious diseases, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 4 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 4 syntheses or guidelines pooled it, 46 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Article
  7. Review
  8. Neurological Complications of Malaria.Current neurology and neuroscience reports · 2022
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Influenza in High-Risk Hosts-Lessons Learned from Animal Models.Cold Spring Harbor perspectives in medicine · 2020
    Review
  18. Malaria and Parasitic Neglected Tropical Diseases: Potential Syndemics with COVID-19?The American journal of tropical medicine and hygiene · 2020
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 4 countries.

Mark G ThompsonInfluenza Division, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA. isq8@cdc.gov
Robert F Breiman
Mary J Hamel
Meghna Desai
Gideon Emukule
Sammy Khagayi
David K Shay
Kathleen Morales
Simon Kariuki
Godfrey M Bigogo
M Kariuki Njenga
Deron C Burton
Frank Odhiambo
Daniel R Feikin
Kayla F Laserson
Mark A Katz
National Influenza Center · MNKenya Medical Research Institute · KECenters for Disease Control and Prevention · KECenters for Disease Control and Prevention · USDivision of Parasitic Diseases and Malaria · US

Funding

KEMRI/CDC ProgramU19CI000323 · CI · KENYA MEDICAL RESEARCH INSTITUTE (KEMRI) · PI VULULE, JOHN MUDEGU · 2005 to 2010
$90.7M
Intramural CDC HHS CC999999NCPDCID CDC HHS 5U19CI000323-05NCPDCID CDC HHS U19 CI000323
6 · The paper itself

Abstract

backgroundAlthough children <5 years old in sub-Saharan Africa are vulnerable to both malaria and influenza, little is known about coinfection.

methodsThis retrospective, cross-sectional study in rural western Kenya examined outpatient visits and hospitalizations associated with febrile acute respiratory illness (ARI) during a 2-year period (July 2009-June 2011) in children <5 years old.

resultsAcross sites, 45% (149/331) of influenza-positive patients were coinfected with malaria, whereas only 6% (149/2408) of malaria-positive patients were coinfected with influenza. Depending on age, coinfection was present in 4%-8% of outpatient visits and 1%-3% of inpatient admissions for febrile ARI. Children with influenza were less likely than those without to have malaria (risk ratio [RR], 0.57-0.76 across sites and ages), and children with malaria were less likely than those without to have influenza (RR, 0.36-0.63). Among coinfected children aged 24-59 months, hospital length of stay was 2.7 and 2.8 days longer than influenza-only-infected children at the 2 sites, and 1.3 and 3.1 days longer than those with malaria only (all P < .01).

conclusionsCoinfection with malaria and influenza was uncommon but associated with longer hospitalization than single infections among children 24-59 months of age.

Indexed as

Child, PreschoolFemaleHIV InfectionsHospitalizationHumansInfantInfant, NewbornInfluenza, HumanKenyaMalariaMaleRisk Factors

Identifiers

PMID22984118
PMCPMC5901689
OpenAlexW2169467339

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.